Gene Symbol | FUT9 |
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Entrez Gene | 10690 |
Alt Symbol | Fuc-TIX |
Species | Human |
Gene Type | protein-coding |
Description | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
Other Description | alpha-(1,3)-fucosyltransferase 9|fucT-IX|fucosyltransferase IX|galactoside 3-L-fucosyltransferase |
Swissprots | Q9Y231 Q5T0W4 |
Accessions | EAW48510 EAW48511 Q9Y231 AB023021 BAA81685 AJ238701 CAB41890 AK095046 AK293817 BAG57222 AK314966 BAG37467 AL080093 AL833558 AY800264 AAV67966 BC001879 AAH01879 BC036101 AAH36101 CK299829 CK904220 DQ894123 ABM85049 XM_011535383 XP_011533685 XM_011535384 XP_011533686 XM_011535385 XP_011533687 NM_006581 NP_006572 |
Function | Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. {ECO:0000269|PubMed:10386598}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}. |
Tissue Specificity | Strongly expressed in forebrain and stomach, lower expression in spleen and peripheral blood leukocytes, and no expression in small intestine, colon, liver, lung, kidney, adrenal cortex or uterus. {ECO:0000269|PubMed:10386598}. |
Top Pathways | Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |
FucT-IX CRISPR/Cas9 KO Plasmid (h) - sc-416354 from Santa Cruz Biotechnology
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FucT-IX HDR Plasmid (h) - sc-416354-HDR from Santa Cruz Biotechnology
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FucT-IX Double Nickase Plasmid (h) - sc-416354-NIC from Santa Cruz Biotechnology
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FucT-IX Double Nickase Plasmid (h2) - sc-416354-NIC-2 from Santa Cruz Biotechnology
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FucT-IX CRISPR Activation Plasmid (h) - sc-416354-ACT from Santa Cruz Biotechnology
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FucT-IX CRISPR Activation Plasmid (h2) - sc-416354-ACT-2 from Santa Cruz Biotechnology
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FucT-IX Lentiviral Activation Particles (h) - sc-416354-LAC from Santa Cruz Biotechnology
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FucT-IX Lentiviral Activation Particles (h2) - sc-416354-LAC-2 from Santa Cruz Biotechnology
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FucT-IX siRNA (h) - sc-40590 from Santa Cruz Biotechnology
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FucT-IX shRNA Plasmid (h) - sc-40590-SH from Santa Cruz Biotechnology
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FucT-IX shRNA (h) Lentiviral Particles - sc-40590-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9005 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9005 from Sigma-Aldrich
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FUT9 siRNA (Human) - CRH7289 from Cohesion Biosciences
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FUT9 - MBS8236388 from MyBioSource
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shRNA set against Human FUT9 (NM_006581.3) - SHH297841 from Creative biogene
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shRNA set against Human FUT9(NM_006581.3) - SHH070895 from Creative biogene
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Human FUT9 siRNA - orb267791 from Biorbyt
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FUT9 shRNA Plasmid (Human) - CHH7289 from Cohesion Biosciences
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FUT9 miRNA 3'UTR clone - MiUTR1H-03883 from Creative biogene
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