| Gene Symbol |
Atp5j
|
| Entrez Gene |
94271
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
|
| Other Description |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6|ATP synthase-coupling factor 6, mitochondrial|ATPase subunit F6|coupling factor 6
|
| Swissprots |
P21571
|
| Accessions |
EDM10624 P21571 BC059121 AAH59121 FQ212150 FQ214305 FQ216982 FQ217271 FQ217448 FQ224472 FQ228382 M73030 AAA40954 X54510 CAA38369 XM_008768600 XP_008766822 XM_008768601 XP_008766823 XM_008768602 XP_008766824 XM_008768603 XP_008766825 NM_053602 NP_446054
|
| Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion. Mitochondrion inner membrane.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Oxidative phosphorylation
|