Gene Symbol | Ids |
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Entrez Gene | 15931 |
Alt Symbol | AW214631 |
Species | Mouse |
Gene Type | protein-coding |
Description | iduronate 2-sulfatase |
Other Description | alpha-L-iduronate sulfate sulfatase|iduronate sulfatase|iduronate-2-sulfatase |
Swissprots | Q3TM30 Q32KI7 Q08890 |
Accessions | EDL26597 Q08890 AF538870 AAN16453 AJ627044 CAF25312 AK085237 AK132287 BAE21082 AK166178 BAE38612 AK166443 BC160215 AAI60215 BN000750 CAI84996 CD740869 L07921 AAA37880 X75636 XM_006527845 XP_006527908 XM_006527846 XP_006527909 NM_001038990 NM_001038991 NM_010498 NP_034628 |
Function | Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. {ECO:0000269|PubMed:15149955}. |
Subcellular Location | Lysosome. |
Tissue Specificity | Found to be expressed in alpha and beta pancreatic cells. {ECO:0000269|PubMed:15149955}. |
Top Pathways | Lysosome, Glycosaminoglycan degradation |
IDS CRISPR/Cas9 KO Plasmid (m) - sc-421025 from Santa Cruz Biotechnology
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IDS HDR Plasmid (m) - sc-421025-HDR from Santa Cruz Biotechnology
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IDS Double Nickase Plasmid (m) - sc-421025-NIC from Santa Cruz Biotechnology
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IDS Double Nickase Plasmid (m2) - sc-421025-NIC-2 from Santa Cruz Biotechnology
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IDS CRISPR Activation Plasmid (m) - sc-421025-ACT from Santa Cruz Biotechnology
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IDS CRISPR Activation Plasmid (m2) - sc-421025-ACT-2 from Santa Cruz Biotechnology
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IDS Lentiviral Activation Particles (m) - sc-421025-LAC from Santa Cruz Biotechnology
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IDS Lentiviral Activation Particles (m2) - sc-421025-LAC-2 from Santa Cruz Biotechnology
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IDS siRNA (m) - sc-146143 from Santa Cruz Biotechnology
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IDS shRNA Plasmid (m) - sc-146143-SH from Santa Cruz Biotechnology
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IDS shRNA (m) Lentiviral Particles - sc-146143-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33611 from Sigma-Aldrich
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IDS siRNA (Mouse) - CRM1991 from Cohesion Biosciences
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IDS - MBS8219213 from MyBioSource
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shRNA set against Mouse IDS (NM_010498.3) - SHH316669 from Creative biogene
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Mouse IDS siRNA - orb281467 from Biorbyt
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IDS shRNA Plasmid (Mouse) - CHM1991 from Cohesion Biosciences
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