Gene Symbol | LIAS |
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Entrez Gene | 11019 |
Alt Symbol | HUSSY-01, LAS, LIP1, LS, PDHLD |
Species | Human |
Gene Type | protein-coding |
Description | lipoic acid synthetase |
Other Description | LS|lip-syn|lipoate synthase|lipoyl synthase, mitochondrial |
Swissprots | Q8IV62 C9JCF6 O43766 A8K873 |
Accessions | CBN72404 CBN72413 EAW92932 EAW92933 EAW92934 O43766 AI373464 AJ224162 CAA11859 AK026289 AK291985 BAF84674 AK292238 BAF84927 AK303429 BAG64479 AL528262 AV729111 BC023635 AAH23635 BC062751 AAH62751 BF434814 HQ447772 ADQ32257 XM_006713990 XP_006714053 NM_001278590 NP_001265519 NM_001278591 NP_001265520 NM_001278592 NP_001265521 NM_006859 NP_006850 NM_194451 NP_919433 |
Function | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}. |
Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}. |
Top Pathways | Lipoic acid metabolism |
LIAS (N-15) - sc-163018 from Santa Cruz Biotechnology
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LIAS (K-14) - sc-163017 from Santa Cruz Biotechnology
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LIAS (S-24) - sc-133739 from Santa Cruz Biotechnology
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LIAS (T-14) - sc-163019 from Santa Cruz Biotechnology
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Anti-LIAS antibody - ab56819 from Abcam
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Anti-LIAS / LIP1 Antibody (clone 1C7) - LS-C133673 from LifeSpan Bioscience
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Anti-LIAS / LIP1 Antibody (aa54-258) - LS-C186406 from LifeSpan Bioscience
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Anti-LIAS / LIP1 Antibody (aa38-87) - LS-C81282 from LifeSpan Bioscience
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Anti-LIAS / LIP1 Antibody (C-Terminus) - LS-C81283 from LifeSpan Bioscience
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LIAS Antibody - NBP1-82845 from Novus Biologicals
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LIAS Antibody - NBP1-54320 from Novus Biologicals
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LIAS Antibody - NBP1-54319 from Novus Biologicals
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LIAS Antibody (1C7) - H00011019-M03 from Novus Biologicals
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Anti-LIAS antibody produced in rabbit - SAB2101343 from Sigma-Aldrich
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Monoclonal Anti-LIAS antibody produced in mouse - WH0011019M3 from Sigma-Aldrich
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Anti-LIAS antibody produced in rabbit - HPA018842 from Sigma-Aldrich
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LIAS antibody - N-terminal region (ARP48716_P050) - ARP48716_P050 from Aviva Systems Biology
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LIAS antibody - C-terminal region (ARP48717_P050) - ARP48717_P050 from Aviva Systems Biology
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lias antibody - zf125024 from GeneTex
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Lipoic acid synthetase antibody [N1C2] - GTX115528 from GeneTex
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LIAS antibody - 70R-2254 from Fitzgerald
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Lipoic acid synthetase antibody - 70R-13648 from Fitzgerald
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Anti -LIAS (LS, LAS, LIP1, PDHLD, HUSSY-01, Lipoyl Synthase, Mitochondrial, LipoateSynthase) - 211758 from USBiological Life Science
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Anti -LIAS (Lipoyl Synthase, Mitochondrial, Lipoate Synthase, LS, Lip-syn, Lipoic AcidSynthase, LAS, HUSSY-01, MGC23245) - 129086 from USBiological Life Science
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Anti -LIAS (Lipoyl Synthase, Mitochondrial, Lipoate Synthase, LS, Lip-syn, Lipoic AcidSynthase, LAS, HUSSY-01, MGC23245) (AP) - 129086-AP from USBiological Life Science
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