Gene Symbol | ALDH3A1 |
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Entrez Gene | 218 |
Alt Symbol | ALDH3, ALDHIII |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 3 family, member A1 |
Other Description | aldehyde dehydrogenase isozyme 3|aldehyde dehydrogenase type III|aldehyde dehydrogenase, dimeric NADP-preferring|stomach aldehyde dehydrogenase |
Swissprots | Q9BT37 P30838 A8K828 |
Accessions | EAW50908 EAW50909 P30838 AK091272 AK093755 BAG52758 AK093877 BAC04239 AK225505 AK225513 AK292193 BAF84882 AK314584 BAG37160 BC004102 AAH04102 BC004370 AAH04370 BC008892 AAH08892 BC021194 AAH21194 BM979497 BT007102 AAP35766 CV575863 DA427150 DA445491 DQ892988 ABM83914 M74542 AAA51696 M77477 AAB46377 S61044 AAB26658 XM_005256522 XP_005256579 XM_005256523 XP_005256580 XM_005256524 XP_005256581 XM_011523730 XP_011522032 XM_011523731 XP_011522033 NM_000691 NP_000682 NM_001135167 NP_001128639 NM_001135168 NP_001128640 |
Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | High levels in stomach, esophagus and lung; low level in the liver and kidney. |
Top Pathways | Chemical carcinogenesis, Glycolysis / Gluconeogenesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tyrosine metabolism |
ALDH3A1-Over-expression-Lysate - LY11481a from Abgent, a WuXi AppTec company
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ALDH3A1 293T Cell Transient Overexpression Lysate(Denatured) - H00000218-T01 from Acris Antibodies
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ALDH3A1 overexpression lysate - LY427569 from Acris Antibodies
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ALDH3A1 overexpression lysate - LY427570 from Acris Antibodies
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ALDH3A1 293 Cell Lysate - 400289 from ABBIOTEC
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Aldehyde Dehydrogenase 3-A1/ALDH3A1 Overexpression Lysate (Denatured) - H00000218-T01 from Novus Biologicals
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Aldehyde Dehydrogenase 3-A1/ALDH3A1 Overexpression Lysate (Native) - NBL1-07455 from Novus Biologicals
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ALDH3A1 (h): 293 Lysate - sc-174768 from Santa Cruz Biotechnology
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ALDH3A1 (h2): 293 Lysate - sc-158256 from Santa Cruz Biotechnology
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ALDH3A1 Over-expression Lysate Product - GWB-FE8B9E from Genway Biotech
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Human ALDH3A1 Insect Cell Lysate (WB positive control) - 12523-H07BL-300 from Sino Biological
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Aldehyde Dehydrogenase 3-A1/ALDH3A1 Overexpression Lysate (Native) - NBP2-09567 from Novus Biologicals
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Aldehyde Dehydrogenase 3-A1/ALDH3A1 Overexpression Lysate (Native) - NBP2-09566 from Novus Biologicals
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Human ALDH3A1 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175078 from Biorbyt
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Panoply™ Human ALDH3A1 Knockdown Stable Cell Line - CSC-DC000483 from Creative biogene
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