Gene Symbol | ABTB1 |
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Entrez Gene | 80325 |
Alt Symbol | BPOZ, BTB3, BTBD21, EF1ABP, PP2259 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and BTB (POZ) domain containing 1 |
Other Description | ankyrin repeat and BTB/POZ domain-containing protein 1|elongation factor 1A-binding protein |
Swissprots | D3DNB0 Q6ZNU9 Q96S62 Q71MF1 Q96S63 Q969K4 |
Accessions | EAW79333 EAW79334 EAW79335 EAW79336 Q969K4 AB053324 BAB55648 AB053325 BAB55649 AB053326 BAB55650 AF297986 AAK57478 AF447886 AAQ04661 AI337369 AK090422 BAC03403 AK090509 AK098738 AK130594 BAC85392 AK315148 BAG37596 BC011858 AAH11858 BF664138 BM671027 XM_006713769 XP_006713832 XM_006713772 XP_006713835 XM_011513212 XP_011511514 XM_011513213 XP_011511515 XR_924182 XR_924183 NM_032548 NP_115937 NM_172027 NP_742024 NR_033429 NM_172028 |
Function | May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. {ECO:0000269|PubMed:10891360, ECO:0000269|PubMed:11494141}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11494141}. |
Tissue Specificity | Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. {ECO:0000269|PubMed:10891360}. |
ABTB1 CRISPR/Cas9 KO Plasmid (h) - sc-408539 from Santa Cruz Biotechnology
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ABTB1 HDR Plasmid (h) - sc-408539-HDR from Santa Cruz Biotechnology
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ABTB1 Double Nickase Plasmid (h) - sc-408539-NIC from Santa Cruz Biotechnology
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ABTB1 Double Nickase Plasmid (h2) - sc-408539-NIC-2 from Santa Cruz Biotechnology
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ABTB1 CRISPR Activation Plasmid (h) - sc-408539-ACT from Santa Cruz Biotechnology
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ABTB1 CRISPR Activation Plasmid (h2) - sc-408539-ACT-2 from Santa Cruz Biotechnology
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ABTB1 Lentiviral Activation Particles (h) - sc-408539-LAC from Santa Cruz Biotechnology
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ABTB1 Lentiviral Activation Particles (h2) - sc-408539-LAC-2 from Santa Cruz Biotechnology
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ABTB1 siRNA (h) - sc-72420 from Santa Cruz Biotechnology
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ABTB1 shRNA Plasmid (h) - sc-72420-SH from Santa Cruz Biotechnology
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ABTB1 shRNA (h) Lentiviral Particles - sc-72420-V from Santa Cruz Biotechnology
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BPOZ RNAi - H00080325-R01 from Novus Biologicals
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MISSION® esiRNA - EHU134781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2682 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2682 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03474 from Sigma-Aldrich
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ABTB1 siRNA (Human) - CRJ2857 from Cohesion Biosciences
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BPOZ RNAi - H00080325-R02 from Novus Biologicals
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BPOZ RNAi - H00080325-R03 from Novus Biologicals
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ABTB1 - MBS8235072 from MyBioSource
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shRNA set against Human ABTB1 (NM_032548.3) - SHH229766 from Creative biogene
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ABTB1 shRNA Plasmid (Human) - CHJ2857 from Cohesion Biosciences
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ABTB1 miRNA 3'UTR clone - MiUTR3H-09908 from Creative biogene
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