Gene Symbol | Prok2 |
---|---|
Entrez Gene | 50501 |
Alt Symbol | Bv8, PK2, Prok1 |
Species | Mouse |
Gene Type | protein-coding |
Description | prokineticin 2 |
Other Description | Bombina variegata 8 kD protein|Bombina variegata 8kDa protein|Bv 8 homolog (Bombina variegata)|prokineticin 1|prokineticin-2|protein Bv8 homolog |
Swissprots | Q9QXU7 Q9QXU5 Q9QXU6 B7ZMX7 |
Accessions | AAG09439 EDK99367 EDK99368 Q9QXU7 AF182064 AAF15259 AF182065 AAF15260 AF182066 AAF15261 AF487280 AAM49572 AK015462 BAB29857 BB614931 BC116911 AAI16912 BC144863 AAI44864 BY232101 NM_001037539 NP_001032628 NM_001170419 NP_001163890 NM_015768 NP_056583 |
Function | May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in the SCN and among a few other discrete brain areas, including the islands of Calleja, media l preoptic area of the hypothalamus and the shell of the nucleus accumbens. Highly expressed in testis. In the SCN, expression subjected to high amplitude of circadian oscillation. |
Prokineticin-2 CRISPR/Cas9 KO Plasmid (m) - sc-424450 from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 HDR Plasmid (m) - sc-424450-HDR from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 Double Nickase Plasmid (m) - sc-424450-NIC from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 Double Nickase Plasmid (m2) - sc-424450-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 CRISPR Activation Plasmid (m) - sc-424450-ACT from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 CRISPR Activation Plasmid (m2) - sc-424450-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 Lentiviral Activation Particles (m) - sc-424450-LAC from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 Lentiviral Activation Particles (m2) - sc-424450-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 siRNA (m) - sc-61410 from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 shRNA Plasmid (m) - sc-61410-SH from Santa Cruz Biotechnology
|
||||||||
Prokineticin-2 shRNA (m) Lentiviral Particles - sc-61410-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU007181 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN39374 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39374 from Sigma-Aldrich
|
||||||||
PROK2 siRNA (Mouse) - CRM5106 from Cohesion Biosciences
|
||||||||
shRNA set against Mouse PROK2 (NM_015768.2) - SHH383512 from Creative biogene
|
||||||||
Mouse PROK2 siRNA - orb284582 from Biorbyt
|
||||||||
PROK2 shRNA Plasmid (Mouse) - CHM5106 from Cohesion Biosciences
|
||||||||