BST1

Gene Symbol BST1
Entrez Gene 683
Alt Symbol CD157
Species Human
Gene Type protein-coding
Description bone marrow stromal cell antigen 1
Other Description ADP-ribosyl cyclase 2|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2|BST-1|NAD(+) nucleosidase|bone marrow stromal antigen 1|cADPr hydrolase 2|cyclic ADP-ribose hydrolase 2
Swissprots Q1XII0 Q96EN3 Q10588 B2R6A2 Q5U0K0
Accessions AAY40930 EAW92744 Q10588 AB175627 BAE92566 AK312497 BAG35399 BC012095 AAH12095 BT019502 AAV38309 BU732655 D21878 BAA04885 DA382561 XM_005248184 XP_005248241 XM_005248185 XP_005248242 XM_005248186 XP_005248243 XM_011513878 XP_011512180 XM_011513879 XP_011512181 XM_011513880 XP_011512182 XM_011513881 XP_011512183 NM_004334 NP_004325
Function Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. {ECO:0000269|PubMed:11866528}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity Widely expressed.
Top Pathways Salivary secretion, Pancreatic secretion, Nicotinate and nicotinamide metabolism