Gene Symbol | BST1 |
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Entrez Gene | 683 |
Alt Symbol | CD157 |
Species | Human |
Gene Type | protein-coding |
Description | bone marrow stromal cell antigen 1 |
Other Description | ADP-ribosyl cyclase 2|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2|BST-1|NAD(+) nucleosidase|bone marrow stromal antigen 1|cADPr hydrolase 2|cyclic ADP-ribose hydrolase 2 |
Swissprots | Q1XII0 Q96EN3 Q10588 B2R6A2 Q5U0K0 |
Accessions | AAY40930 EAW92744 Q10588 AB175627 BAE92566 AK312497 BAG35399 BC012095 AAH12095 BT019502 AAV38309 BU732655 D21878 BAA04885 DA382561 XM_005248184 XP_005248241 XM_005248185 XP_005248242 XM_005248186 XP_005248243 XM_011513878 XP_011512180 XM_011513879 XP_011512181 XM_011513880 XP_011512182 XM_011513881 XP_011512183 NM_004334 NP_004325 |
Function | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. {ECO:0000269|PubMed:11866528}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Widely expressed. |
Top Pathways | Salivary secretion, Pancreatic secretion, Nicotinate and nicotinamide metabolism |
BST-1 CRISPR/Cas9 KO Plasmid (h) - sc-409468 from Santa Cruz Biotechnology
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BST-1 HDR Plasmid (h) - sc-409468-HDR from Santa Cruz Biotechnology
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BST-1 Double Nickase Plasmid (h) - sc-409468-NIC from Santa Cruz Biotechnology
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BST-1 Double Nickase Plasmid (h2) - sc-409468-NIC-2 from Santa Cruz Biotechnology
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BST-1 CRISPR Activation Plasmid (h) - sc-409468-ACT from Santa Cruz Biotechnology
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BST-1 CRISPR Activation Plasmid (h2) - sc-409468-ACT-2 from Santa Cruz Biotechnology
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BST-1 Lentiviral Activation Particles (h) - sc-409468-LAC from Santa Cruz Biotechnology
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BST-1 Lentiviral Activation Particles (h2) - sc-409468-LAC-2 from Santa Cruz Biotechnology
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BST-1 siRNA (h) - sc-43643 from Santa Cruz Biotechnology
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BST-1 shRNA Plasmid (h) - sc-43643-SH from Santa Cruz Biotechnology
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BST-1 shRNA (h) Lentiviral Particles - sc-43643-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU149081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4082 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4082 from Sigma-Aldrich
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BST1 siRNA (Human) - CRH0475 from Cohesion Biosciences
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BST1 - MBS8201678 from MyBioSource
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shRNA set against Human BST1 (NM_004334.2) - SHH248006 from Creative biogene
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shRNA set against Human BST1(NM_004334.2) - SHG106261 from Creative biogene
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Human BST1 siRNA - orb260977 from Biorbyt
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BST1 shRNA Plasmid (Human) - CHH0475 from Cohesion Biosciences
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BST1 miRNA 3'UTR clone - MiUTR1H-00959 from Creative biogene
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