Gene Symbol | OSTM1 |
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Entrez Gene | 28962 |
Alt Symbol | GIPN, GL, HSPC019, OPTB5 |
Species | Human |
Gene Type | protein-coding |
Description | osteopetrosis associated transmembrane protein 1 |
Other Description | CLCN7 accessory beta subunit|GAIP-interacting protein N terminus|chloride channel 7 beta subunit|grey-lethal osteopetrosis|osteopetrosis-associated transmembrane protein 1 |
Swissprots | Q86WC4 Q8NC29 Q7RTW6 Q6PCA7 Q5R391 Q8TC82 Q9Y2S9 E1P5E3 |
Accessions | EAW48389 EAW48390 EAW48391 Q86WC4 AA428166 AF077205 AAD27000 AF533891 AAO72749 AJ420489 AJ420572 AK075012 BAC11351 AK129854 AK314393 AV715475 AY358795 AAQ89155 BC010845 BC016376 BC059412 BC068581 AAH68581 BE218267 BI668275 BK000461 DAA00039 BQ716123 XM_011535775 XP_011534077 XM_011535776 XP_011534078 XR_942410 NM_014028 NP_054747 |
Function | Required for osteoclast and melanocyte maturation and function. {ECO:0000250}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:21527911}; Single-pass type I membrane protein {ECO:0000269|PubMed:21527911}. Note=Requires CLCN7 to travel to lysosomes. |
OSTM1 CRISPR/Cas9 KO Plasmid (h) - sc-405465 from Santa Cruz Biotechnology
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OSTM1 HDR Plasmid (h) - sc-405465-HDR from Santa Cruz Biotechnology
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OSTM1 Double Nickase Plasmid (h) - sc-405465-NIC from Santa Cruz Biotechnology
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OSTM1 Double Nickase Plasmid (h2) - sc-405465-NIC-2 from Santa Cruz Biotechnology
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OSTM1 CRISPR Activation Plasmid (h) - sc-405465-ACT from Santa Cruz Biotechnology
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OSTM1 CRISPR Activation Plasmid (h2) - sc-405465-ACT-2 from Santa Cruz Biotechnology
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OSTM1 Lentiviral Activation Particles (h) - sc-405465-LAC from Santa Cruz Biotechnology
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OSTM1 Lentiviral Activation Particles (h2) - sc-405465-LAC-2 from Santa Cruz Biotechnology
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OSTM1 siRNA (h) - sc-95126 from Santa Cruz Biotechnology
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OSTM1 shRNA Plasmid (h) - sc-95126-SH from Santa Cruz Biotechnology
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OSTM1 shRNA (h) Lentiviral Particles - sc-95126-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU087651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16183 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16183 from Sigma-Aldrich
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OSTM1 siRNA (Human) - CRH9130 from Cohesion Biosciences
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shRNA set against Human OSTM1 (NM_014028.3) - SHH368908 from Creative biogene
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Human OSTM1 siRNA - orb269632 from Biorbyt
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OSTM1 shRNA Plasmid (Human) - CHH9130 from Cohesion Biosciences
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OSTM1 miRNA 3'UTR clone - MiUTR1H-07407 from Creative biogene
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