Gene Symbol | NOG |
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Entrez Gene | 9241 |
Alt Symbol | SYM1, SYNS1 |
Species | Human |
Gene Type | protein-coding |
Description | noggin |
Other Description | symphalangism 1 (proximal) |
Swissprots | Q13253 |
Accessions | AAA83259 CEF39439 EAW94528 Q13253 AK314080 BAG36778 BC034027 AAH34027 NM_005450 NP_005441 |
Function | Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. {ECO:0000269|PubMed:12478285}. |
Subcellular Location | Secreted. |
Top Pathways | TGF-beta signaling pathway |
Noggin CRISPR/Cas9 KO Plasmid (h) - sc-402090 from Santa Cruz Biotechnology
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Noggin HDR Plasmid (h) - sc-402090-HDR from Santa Cruz Biotechnology
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Noggin Double Nickase Plasmid (h) - sc-402090-NIC from Santa Cruz Biotechnology
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Noggin Double Nickase Plasmid (h2) - sc-402090-NIC-2 from Santa Cruz Biotechnology
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Noggin CRISPR Activation Plasmid (h) - sc-402090-ACT from Santa Cruz Biotechnology
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Noggin CRISPR Activation Plasmid (h2) - sc-402090-ACT-2 from Santa Cruz Biotechnology
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Noggin Lentiviral Activation Particles (h) - sc-402090-LAC from Santa Cruz Biotechnology
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Noggin Lentiviral Activation Particles (h2) - sc-402090-LAC-2 from Santa Cruz Biotechnology
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Noggin siRNA (h) - sc-42138 from Santa Cruz Biotechnology
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Noggin shRNA Plasmid (h) - sc-42138-SH from Santa Cruz Biotechnology
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Noggin shRNA (h) Lentiviral Particles - sc-42138-V from Santa Cruz Biotechnology
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Noggin RNAi - H00009241-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15395 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15395 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02276 from Sigma-Aldrich
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NOG siRNA (Human) - CRH6117 from Cohesion Biosciences
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shRNA set against Human NOG (NM_005450.4) - SHH353476 from Creative biogene
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shRNA set against Human NOG(NM_005450.4) - SHR015234 from Creative biogene
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Noggin CRISPR/Cas9 KO Plasmid (h2) - sc-402090-KO-2 from Santa Cruz Biotechnology
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Noggin HDR Plasmid (h2) - sc-402090-HDR-2 from Santa Cruz Biotechnology
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Human NOG siRNA - orb266619 from Biorbyt
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NOG shRNA Plasmid (Human) - CHH6117 from Cohesion Biosciences
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NOG miRNA 3'UTR clone - MiUTR1H-06833 from Creative biogene
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