Gene Symbol | IL12A |
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Entrez Gene | 3592 |
Alt Symbol | CLMF, IL-12A, NFSK, NKSF1, P35 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 12A |
Other Description | CLMF p35|IL-12, subunit p35|IL35 subunit|NF cell stimulatory factor chain 1|NK cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|cytotoxic lymphocyte maturation factor 35 kDa subunit|interleukin 12, p35|interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)|interleukin-12 alpha chain|interleukin-12 subunit alpha |
Swissprots | P29459 Q96QZ1 |
Accessions | AAC05211 AAC05212 AAK84425 CAM82732 CBX32667 CCA63969 EAW78656 EAW78657 EAW78658 P29459 AF101062 AAD16432 AF180562 AAD56385 AW472810 BC035571 BC104982 AAI04983 BC104984 AAI04985 BG702253 M65271 AAA35694 M65291 AAA59937 NM_000882 NP_000873 |
Function | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. |
Subcellular Location | Secreted. |
Top Pathways | Herpes simplex infection, Malaria, Tuberculosis, Influenza A, Measles |
IL-12A p35 CRISPR/Cas9 KO Plasmid (h) - sc-416569 from Santa Cruz Biotechnology
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IL-12A p35 HDR Plasmid (h) - sc-416569-HDR from Santa Cruz Biotechnology
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IL-12A p35 Double Nickase Plasmid (h) - sc-416569-NIC from Santa Cruz Biotechnology
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IL-12A p35 Double Nickase Plasmid (h2) - sc-416569-NIC-2 from Santa Cruz Biotechnology
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IL-12A p35 CRISPR Activation Plasmid (h) - sc-416569-ACT from Santa Cruz Biotechnology
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IL-12A p35 CRISPR Activation Plasmid (h2) - sc-416569-ACT-2 from Santa Cruz Biotechnology
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IL-12A p35 Lentiviral Activation Particles (h) - sc-416569-LAC from Santa Cruz Biotechnology
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IL-12A p35 Lentiviral Activation Particles (h2) - sc-416569-LAC-2 from Santa Cruz Biotechnology
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IL-12A p35 siRNA (h) - sc-39638 from Santa Cruz Biotechnology
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IL-12A p35 shRNA Plasmid (h) - sc-39638-SH from Santa Cruz Biotechnology
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IL-12A p35 shRNA (h) Lentiviral Particles - sc-39638-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU014611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10565 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10565 from Sigma-Aldrich
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IL12A siRNA (Human) - CRH2401 from Cohesion Biosciences
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IL12A - MBS8224989 from MyBioSource
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shRNA set against Human IL12A (NM_000882.3) - SHH318177 from Creative biogene
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IL12A shRNA Plasmid (Human) - CHH2401 from Cohesion Biosciences
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IL12A miRNA 3'UTR clone - MiUTR3H-01514 from Creative biogene
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