| Gene Symbol |
KIF20A
|
| Entrez Gene |
10112
|
| Alt Symbol |
MKLP2, RAB6KIFL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 20A
|
| Other Description |
GG10_2|RAB6 interacting, kinesin-like (rabkinesin6)|kinesin-like protein KIF20A|mitotic kinesin-like protein 2|rab6-interacting kinesin-like protein|rabkinesin-6
|
| Swissprots |
B4DL79 D3DQB6 O95235
|
| Accessions |
CBX51350 CCQ77691 CCQ77700 CCQ77709 CCQ77718 CDH48197 CDH61619 CDH61673 CDH61692 CDH88990 CDH92528 CDH92542 CDH92553 CDH92800 CDH92897 CDI44672 CDI44681 EAW62157 EAW62158 O95235 AF070672 AAC83230 AF153329 AAD37806 AK024804 AK025790 AK296879 BAG59441 AM392783 CAL37661 BC012999 AAH12999 DC402781 XR_948224 NM_005733 NP_005724
|
| Function |
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. {ECO:0000269|PubMed:12939256}.
|
| Subcellular Location |
Golgi apparatus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:12939256}.
|