Gene Symbol | MVD |
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Entrez Gene | 4597 |
Alt Symbol | FP17780, MDDase, MPD |
Species | Human |
Gene Type | protein-coding |
Description | mevalonate (diphospho) decarboxylase |
Other Description | diphosphomevalonate decarboxylase|mevalonate pyrophosphate decarboxylase |
Swissprots | Q53Y65 P53602 |
Accessions | EAW66790 EAW66791 EAW66792 P53602 AB209229 BAD92466 AY203927 AAP34450 BC000011 AAH00011 BI752043 BT006930 AAP35576 DQ890562 ABM92179 DQ893724 ABM84650 HY026498 U49260 AAC50440 XM_011523086 XP_011521388 XM_011523087 XP_011521389 XM_011523088 XP_011521390 XM_011523089 XP_011521391 XM_011523090 XP_011521392 NM_002461 NP_002452 |
Function | Performs the first committed step in the biosynthesis of isoprenes. |
Tissue Specificity | Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. {ECO:0000269|PubMed:8626466}. |
Top Pathways | Terpenoid backbone biosynthesis |
MVD CRISPR/Cas9 KO Plasmid (h) - sc-408485 from Santa Cruz Biotechnology
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MVD HDR Plasmid (h) - sc-408485-HDR from Santa Cruz Biotechnology
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MVD Double Nickase Plasmid (h) - sc-408485-NIC from Santa Cruz Biotechnology
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MVD Double Nickase Plasmid (h2) - sc-408485-NIC-2 from Santa Cruz Biotechnology
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MVD CRISPR Activation Plasmid (h) - sc-408485-ACT from Santa Cruz Biotechnology
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MVD CRISPR Activation Plasmid (h2) - sc-408485-ACT-2 from Santa Cruz Biotechnology
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MVD Lentiviral Activation Particles (h) - sc-408485-LAC from Santa Cruz Biotechnology
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MVD Lentiviral Activation Particles (h2) - sc-408485-LAC-2 from Santa Cruz Biotechnology
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MVD siRNA (h) - sc-93276 from Santa Cruz Biotechnology
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MVD shRNA Plasmid (h) - sc-93276-SH from Santa Cruz Biotechnology
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MVD shRNA (h) Lentiviral Particles - sc-93276-V from Santa Cruz Biotechnology
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MVD RNAi - H00004597-R02 from Novus Biologicals
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MISSION® esiRNA - EHU030571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14776 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14776 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04978 from Sigma-Aldrich
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MVD siRNA (Human) - CRH3028 from Cohesion Biosciences
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shRNA set against Human MVD (NM_002461.1) - SHH347244 from Creative biogene
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Human MVD siRNA - orb263530 from Biorbyt
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MVD shRNA Plasmid (Human) - CHH3028 from Cohesion Biosciences
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MVD miRNA 3'UTR clone - MiUTR1H-06538 from Creative biogene
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