Gene Symbol | CCSAP |
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Entrez Gene | 126731 |
Alt Symbol | C1orf96, CSAP |
Species | Human |
Gene Type | protein-coding |
Description | centriole, cilia and spindle-associated protein |
Other Description | centriole and spindle-associated protein |
Swissprots | Q6P9G2 Q96BM2 Q6IQ19 A8K5X2 Q6ZW85 Q8IXU1 |
Accessions | EAW69897 Q6IQ19 AK094615 AK123465 BAC85619 AK291437 BAF84126 BC015419 AAH15419 BC039241 AAH39241 BC060777 AAH60777 BC071609 AAH71609 XM_011544056 XP_011542358 NM_145257 NP_660300 |
Function | May play a role in embryonic development. May be required for proper cilia beating (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22493317}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:22493317}. Cell projection, axon {ECO:0000269|PubMed:22493317}. Cell projection, cilium {ECO:0000269|PubMed:22493317}. Note=Localizes to two to four centrioles throughout the cell cycle. Localizes to mitotic spindle microtubules during prometaphase and throughout the remainder of mitosis. Localizes to cytoskeleton on interphase. Localizes at the ciliary transition zone which connects the basal bodies to ciliary microtubules. Colocalizes with polyglutamylated tubulin. |
CSAP CRISPR/Cas9 KO Plasmid (h) - sc-414284 from Santa Cruz Biotechnology
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CSAP HDR Plasmid (h) - sc-414284-HDR from Santa Cruz Biotechnology
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CSAP Double Nickase Plasmid (h) - sc-414284-NIC from Santa Cruz Biotechnology
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CSAP Double Nickase Plasmid (h2) - sc-414284-NIC-2 from Santa Cruz Biotechnology
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CSAP CRISPR Activation Plasmid (h) - sc-414284-ACT from Santa Cruz Biotechnology
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CSAP CRISPR Activation Plasmid (h2) - sc-414284-ACT-2 from Santa Cruz Biotechnology
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CSAP Lentiviral Activation Particles (h) - sc-414284-LAC from Santa Cruz Biotechnology
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CSAP Lentiviral Activation Particles (h2) - sc-414284-LAC-2 from Santa Cruz Biotechnology
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CSAP siRNA (h) - sc-78793 from Santa Cruz Biotechnology
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CSAP shRNA Plasmid (h) - sc-78793-SH from Santa Cruz Biotechnology
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CSAP shRNA (h) Lentiviral Particles - sc-78793-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4680 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4680 from Sigma-Aldrich
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CCSAP siRNA (Human) - CRJ4881 from Cohesion Biosciences
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CCSAP - MBS8218546 from MyBioSource
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shRNA set against Human C1orf96 (NM_145257.3) - SHH250661 from Creative biogene
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Human CCSAP siRNA - orb275382 from Biorbyt
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CCSAP shRNA Plasmid (Human) - CHJ4881 from Cohesion Biosciences
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CCSAP miRNA 3'UTR clone - MiUTR4H-TG00916 from Creative biogene
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