Gene Symbol | DSCAML1 |
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Entrez Gene | 57453 |
Alt Symbol | DSCAM2 |
Species | Human |
Gene Type | protein-coding |
Description | Down syndrome cell adhesion molecule like 1 |
Other Description | DSCAM-like 1|Down syndrome cell adhesion molecule-like protein 1|Downs syndrome cell adhesion molecule like 1|down syndrome cell adhesion molecule 2 |
Swissprots | Q9ULT7 Q8TD84 Q76MU9 Q8WXU7 Q8IZY4 Q8IZY3 |
Accessions | EAW67322 EAW67323 Q8TD84 AB032958 BAA86446 AF304304 AAN32613 AF304305 AAN32614 AF334384 AAL57166 AF491813 AAM09558 AK025940 BC156376 AAI56377 BM665756 XM_011542917 XP_011541219 XM_011542918 XP_011541220 XM_011542919 XP_011541221 XM_011542920 XP_011541222 XM_011542921 XP_011541223 XM_011542922 XP_011541224 XM_011542923 XP_011541225 XM_011542924 XP_011541226 XM_011542925 XP_011541227 NM_020693 NP_065744 |
Function | Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus. {ECO:0000269|PubMed:11453658, ECO:0000269|PubMed:12051741}. |
DSCAML1 CRISPR/Cas9 KO Plasmid (h) - sc-409552 from Santa Cruz Biotechnology
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DSCAML1 HDR Plasmid (h) - sc-409552-HDR from Santa Cruz Biotechnology
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DSCAML1 Double Nickase Plasmid (h) - sc-409552-NIC from Santa Cruz Biotechnology
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DSCAML1 Double Nickase Plasmid (h2) - sc-409552-NIC-2 from Santa Cruz Biotechnology
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DSCAML1 CRISPR Activation Plasmid (h) - sc-409552-ACT from Santa Cruz Biotechnology
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DSCAML1 CRISPR Activation Plasmid (h2) - sc-409552-ACT-2 from Santa Cruz Biotechnology
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DSCAML1 Lentiviral Activation Particles (h) - sc-409552-LAC from Santa Cruz Biotechnology
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DSCAML1 Lentiviral Activation Particles (h2) - sc-409552-LAC-2 from Santa Cruz Biotechnology
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DSCAML1 siRNA (h) - sc-96383 from Santa Cruz Biotechnology
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DSCAML1 shRNA Plasmid (h) - sc-96383-SH from Santa Cruz Biotechnology
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DSCAML1 shRNA (h) Lentiviral Particles - sc-96383-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7499 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7499 from Sigma-Aldrich
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DSCAML1 siRNA (Human) - CRJ1448 from Cohesion Biosciences
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DSCAML1 - MBS827554 from MyBioSource
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shRNA set against Human DSCAML1 (NM_020693.2) - SHH281165 from Creative biogene
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shRNA set against Human DSCAML1(NM_020693.2) - SHH016247 from Creative biogene
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Human DSCAML1 siRNA - orb271949 from Biorbyt
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DSCAML1 shRNA Plasmid (Human) - CHJ1448 from Cohesion Biosciences
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DSCAML1 miRNA 3'UTR clone - MiUTR1H-03001 from Creative biogene
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