Gene Symbol | EHD4 |
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Entrez Gene | 30844 |
Alt Symbol | PAST4 |
Species | Human |
Gene Type | protein-coding |
Description | EH-domain containing 4 |
Other Description | EH domain containing 4|EH domain-containing protein 4|PAST homolog 4|hepatocellular carcinoma-associated protein 10/11|hepatocellular carcinoma-associated protein HCA11|ortholog of rat pincher |
Swissprots | Q9NZN2 Q9HAR1 Q9H223 |
Accessions | EAW92525 EAW92526 Q9H223 AF086163 AF181265 AAF40472 AF307137 AAG28784 AF323924 AAK11599 AF454953 AAL51079 AK024902 AK074621 AK292634 BAF85323 BC006287 AAH06287 BC051823 AAH51823 BC077716 BP314075 CF541306 DQ892745 ABM83671 DQ895991 ABM86944 NM_139265 NP_644670 |
Function | Plays a role in early endosomal transport. {ECO:0000269|PubMed:17233914, ECO:0000269|PubMed:18331452}. |
Subcellular Location | Cell membrane {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:18331452}; Peripheral membrane protein {ECO:0000269|PubMed:18331452}. Recycling endosome membrane {ECO:0000269|PubMed:18331452}; Peripheral membrane protein {ECO:0000269|PubMed:18331452}. |
Tissue Specificity | Highly expressed in pancreas and heart. |
Top Pathways | Endocytosis |
EHD4 CRISPR/Cas9 KO Plasmid (h) - sc-408874 from Santa Cruz Biotechnology
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EHD4 HDR Plasmid (h) - sc-408874-HDR from Santa Cruz Biotechnology
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EHD4 Double Nickase Plasmid (h) - sc-408874-NIC from Santa Cruz Biotechnology
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EHD4 Double Nickase Plasmid (h2) - sc-408874-NIC-2 from Santa Cruz Biotechnology
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EHD4 CRISPR Activation Plasmid (h) - sc-408874-ACT from Santa Cruz Biotechnology
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EHD4 CRISPR Activation Plasmid (h2) - sc-408874-ACT-2 from Santa Cruz Biotechnology
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EHD4 Lentiviral Activation Particles (h) - sc-408874-LAC from Santa Cruz Biotechnology
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EHD4 Lentiviral Activation Particles (h2) - sc-408874-LAC-2 from Santa Cruz Biotechnology
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EHD4 siRNA (h) - sc-40521 from Santa Cruz Biotechnology
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EHD4 shRNA Plasmid (h) - sc-40521-SH from Santa Cruz Biotechnology
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EHD4 shRNA (h) Lentiviral Particles - sc-40521-V from Santa Cruz Biotechnology
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EHD4 RNAi - H00030844-R01 from Novus Biologicals
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MISSION® esiRNA - EHU036051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7725 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7725 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08515 from Sigma-Aldrich
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EHD4 siRNA (Human) - CRH9355 from Cohesion Biosciences
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EHD4 - MBS8209429 from MyBioSource
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shRNA set against Human Ehd4 (NM_139265.3) - SHH284009 from Creative biogene
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Human EHD4 siRNA - orb269857 from Biorbyt
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EHD4 shRNA Plasmid (Human) - CHH9355 from Cohesion Biosciences
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EHD4 miRNA 3'UTR clone - MiUTR3H-08024 from Creative biogene
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