Gene Symbol | BARX1 |
---|---|
Entrez Gene | 56033 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | BARX homeobox 1 |
Other Description | BarH-like homeobox 1|homeobox protein BarH-like 1 |
Swissprots | Q9HBU1 Q96GH8 Q6P2R4 |
Accessions | EAW62873 Q9HBU1 AF213356 AAG23738 BC009458 AAH09458 BC064363 AAH64363 JF432442 ADZ15659 NM_021570 NP_067545 |
Function | Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter. {ECO:0000250, ECO:0000269|PubMed:9804553}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal liver. |