Gene Symbol |
Hnf4a
|
Entrez Gene |
25735
|
Alt Symbol |
Hnf4, Hnf4alpha
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
hepatocyte nuclear factor 4, alpha
|
Other Description |
HNF-4-alpha|TCF-14|alpha transcription factor 4|hepatic nuclear factor 4, alpha|hepatocyte nuclear factor 4-alpha|nuclear receptor subfamily 2 group A member 1|transcription factor 14|transcription factor HNF-4
|
Swissprots |
P22449 A2ICG9
|
Accessions |
EDL96572 EDL96573 P22449 AF329936 AAK39433 CK483260 D10554 BAA01411 EF193390 ABM69088 EF193392 ABM69090 FJ608816 ACM50916 FJ608817 ACM50917 FJ608818 ACM50918 FM042560 FQ095211 FQ209887 X57133 CAA40412 XM_006235515 XP_006235577 XM_006235516 XP_006235578 NM_001270931 NP_001257860 NM_001270933 NP_001257862 NM_022180 NP_071516
|
Function |
Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
Liver, kidney and intestine.
|
Top Pathways |
Maturity onset diabetes of the young, AMPK signaling pathway
|