| Gene Symbol |
AK3
|
| Entrez Gene |
50808
|
| Alt Symbol |
AK3L1, AK6, AKL3L, AKL3L1, FIX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adenylate kinase 3
|
| Other Description |
GTP:AMP phosphotransferase AK3, mitochondrial|GTP:AMP phosphotransferase, mitochondrial|adenylate kinase 3 alpha-like 1|adenylate kinase 6, adenylate kinase 3 like 1
|
| Swissprots |
B4DP58 Q9UIJ7 Q9HC01 Q9H576 E7ET30 D3DRI1 Q9NPB4 Q5VYW6
|
| Accessions |
EAW58779 EAW58780 EAW58781 Q9UIJ7 AB021870 BAA87913 AF086913 AAP97143 AF100785 AAP97224 AF183419 AAG09688 AK001553 BAA91753 AK001951 BAA91996 AK027534 BAB55183 AK098205 BAG53592 AK124824 BAG54101 AK298200 BAG60470 BC013771 AAH13771 BI550730 BI601245 BX640794 DA570364 DA718987 DQ891660 ABM82586 DQ894847 ABM85773 NM_001199852 NP_001186781 NM_001199853 NP_001186782 NM_001199855 NP_001186784 NM_001199856 NP_001186785 NM_016282 NP_057366 NM_001199854
|
| Function |
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. {ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|PubMed:11485571}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03169, ECO:0000269|PubMed:11485571}.
|
| Tissue Specificity |
Highly expressed in heart, skeletal muscle and liver, moderately expressed in pancreas and kidney, and weakly expressed in placenta, brain and lung. {ECO:0000269|PubMed:11485571}.
|
| Top Pathways |
Purine metabolism
|