Gene Symbol | SCO1 |
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Entrez Gene | 6341 |
Alt Symbol | SCOD1 |
Species | Human |
Gene Type | protein-coding |
Description | SCO1 cytochrome c oxidase assembly protein |
Other Description | SCO cytochrome oxidase deficient homolog 1|protein SCO1 homolog, mitochondrial |
Swissprots | O75880 B2RDM0 |
Accessions | AAG23836 EAW89997 O75880 AF026852 AAD08641 AF131816 AAD20051 AF183424 AAG09693 AK074588 BAG51973 AK098826 AK315595 BAG37967 BC015504 AAH15504 BM981070 BM994602 DA571370 DQ891605 ABM82531 DQ894798 ABM85724 XM_005256751 XP_005256808 NM_004589 NP_004580 |
Function | Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX. {ECO:0000269|PubMed:15659396, ECO:0000269|PubMed:16735468, ECO:0000269|PubMed:17189203}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:9878253}. |
Tissue Specificity | Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain. {ECO:0000269|PubMed:9878253}. |
SCO1 CRISPR/Cas9 KO Plasmid (h) - sc-409680 from Santa Cruz Biotechnology
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SCO1 HDR Plasmid (h) - sc-409680-HDR from Santa Cruz Biotechnology
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SCO1 Double Nickase Plasmid (h) - sc-409680-NIC from Santa Cruz Biotechnology
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SCO1 Double Nickase Plasmid (h2) - sc-409680-NIC-2 from Santa Cruz Biotechnology
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SCO1 CRISPR Activation Plasmid (h) - sc-409680-ACT from Santa Cruz Biotechnology
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SCO1 CRISPR Activation Plasmid (h2) - sc-409680-ACT-2 from Santa Cruz Biotechnology
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SCO1 Lentiviral Activation Particles (h) - sc-409680-LAC from Santa Cruz Biotechnology
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SCO1 Lentiviral Activation Particles (h2) - sc-409680-LAC-2 from Santa Cruz Biotechnology
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SCO1 siRNA (h) - sc-61505 from Santa Cruz Biotechnology
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SCO1 shRNA Plasmid (h) - sc-61505-SH from Santa Cruz Biotechnology
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SCO1 shRNA (h) Lentiviral Particles - sc-61505-V from Santa Cruz Biotechnology
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SCO1 RNAi - H00006341-R01 from Novus Biologicals
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MISSION® esiRNA - EHU035501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18961 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13035 from Sigma-Aldrich
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SCO1 siRNA (Human) - CRH4276 from Cohesion Biosciences
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SCO1 - MBS8232294 from MyBioSource
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shRNA set against Human SCO1 (NM_004589.2) - SHH402980 from Creative biogene
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SCO1 shRNA Plasmid (Human) - CHH4276 from Cohesion Biosciences
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SCO1 miRNA 3'UTR clone - MiUTR3H-06150 from Creative biogene
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