| Gene Symbol |
GJA1
|
| Entrez Gene |
281193
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
gap junction protein, alpha 1, 43kDa
|
| Other Description |
connexin-43|cx43|gap junction alpha-1 protein|gap junction protein, alpha 1, 43 kD (connexin 43)|vascular smooth muscle connexin-43
|
| Swissprots |
P18246 Q2KJ91
|
| Accessions |
DAA26329 P18246 BC105464 AAI05465 J05535 AAA30459 NM_174068 NP_776493
|
| Function |
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
|
| Top Pathways |
Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC)
|
![Anti-Connexin 43 / GJA1 antibody [4E6.2] (ab79010) at 1/1000 dilution + Rat brain lysate at 10 µgSecondaryGoat anti-mouse HRP](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_2/828_Connexin-43-GJA1-Primary-antibodies-ab79010-3.gif)
