| Gene Symbol | Rhoc |
|---|---|
| Entrez Gene | 11853 |
| Alt Symbol | AI324259, Arh9, Arhc |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | ras homolog gene family, member C |
| Other Description | SIG-61|aplysia ras-related homolog 9 (RhoC)|ras homolog 9 (RhoC)|rho-related GTP-binding protein RhoC|silica-induced gene 61 protein |
| Swissprots | Q3TUN0 Q62159 |
| Accessions | EDL07561 EDL07562 EDL07563 EDL07564 EDL07565 Q62159 AI324259 AK011599 BAB27724 AK152802 BAE31507 AK160650 BAE35941 AK206086 BC004627 AAH04627 BY147599 BY315470 CO044736 CX223083 X80638 CAA56682 NM_001291859 NP_001278788 NM_007484 NP_031510 |
| Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. {ECO:0000269|PubMed:20974804}. |
| Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cleavage furrow {ECO:0000250}. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. {ECO:0000250}. |