Gene Symbol | Rhoc |
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Entrez Gene | 11853 |
Alt Symbol | AI324259, Arh9, Arhc |
Species | Mouse |
Gene Type | protein-coding |
Description | ras homolog gene family, member C |
Other Description | SIG-61|aplysia ras-related homolog 9 (RhoC)|ras homolog 9 (RhoC)|rho-related GTP-binding protein RhoC|silica-induced gene 61 protein |
Swissprots | Q3TUN0 Q62159 |
Accessions | EDL07561 EDL07562 EDL07563 EDL07564 EDL07565 Q62159 AI324259 AK011599 BAB27724 AK152802 BAE31507 AK160650 BAE35941 AK206086 BC004627 AAH04627 BY147599 BY315470 CO044736 CX223083 X80638 CAA56682 NM_001291859 NP_001278788 NM_007484 NP_031510 |
Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. {ECO:0000269|PubMed:20974804}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cleavage furrow {ECO:0000250}. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. {ECO:0000250}. |
Rho C CRISPR/Cas9 KO Plasmid (m) - sc-419196 from Santa Cruz Biotechnology
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Rho C HDR Plasmid (m) - sc-419196-HDR from Santa Cruz Biotechnology
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Rho C Double Nickase Plasmid (m) - sc-419196-NIC from Santa Cruz Biotechnology
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Rho C Double Nickase Plasmid (m2) - sc-419196-NIC-2 from Santa Cruz Biotechnology
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Rho C CRISPR Activation Plasmid (m) - sc-419196-ACT from Santa Cruz Biotechnology
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Rho C CRISPR Activation Plasmid (m2) - sc-419196-ACT-2 from Santa Cruz Biotechnology
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Rho C Lentiviral Activation Particles (m) - sc-419196-LAC from Santa Cruz Biotechnology
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Rho C Lentiviral Activation Particles (m2) - sc-419196-LAC-2 from Santa Cruz Biotechnology
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Rho C siRNA (m) - sc-41888 from Santa Cruz Biotechnology
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Rho C shRNA Plasmid (m) - sc-41888-SH from Santa Cruz Biotechnology
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Rho C shRNA (m) Lentiviral Particles - sc-41888-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU029681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40188 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40188 from Sigma-Aldrich
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RHOC siRNA (Mouse) - CRM0253 from Cohesion Biosciences
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RHOC - MBS8228851 from MyBioSource
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shRNA set against Mouse Rhoc (NM_007484.2) - SHH395328 from Creative biogene
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shRNA set against Mouse Rhoc(NM_007484.2) - SHR180942 from Creative biogene
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RHOC shRNA Plasmid (Mouse) - CHM0253 from Cohesion Biosciences
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RHOC miRNA 3'UTR clone - MiUTR1M-10095 from Creative biogene
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