Gene Symbol |
PPIAL4A
|
Entrez Gene |
653505
|
Alt Symbol |
COAS-2, COAS2, PPIAL4, PPIAL4B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
peptidylprolyl isomerase A (cyclophilin A)-like 4A
|
Other Description |
PPIase A-like 4B|PPIase A-like 4G|chromosome 1-amplified sequence 2|cyclophilin homolog overexpressed in liver cancer|cyclophilin-LC (COAS2)|peptidyl-prolyl cis-trans isomerase A-like 4A/B/C|peptidylprolyl cis-trans isomerase A-like 4A|peptidylprolyl cis-trans isomerase A-like 4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B
|
Swissprots |
Q9Y536
|
Accessions |
CAB46877 CAI18814 Q9Y536 AB084917 BAB92073 BC172332 AAI72332 NM_001143883 NP_001137355
|
Function |
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in brain, ovary and mammary gland. Moderately expressed in lung, salivary gland, kidney, skin, adipose tissue, intestine and spleen. Weakly expressed in skeletal muscle, liver and stomach. Expressed in pleiomorphic and undifferentiated liposarcomas, osteosarcomas and breast carcinomas. {ECO:0000269|PubMed:11948409}.
|