| Gene Symbol |
DSC1
|
| Entrez Gene |
281127
|
| Alt Symbol |
DG2/DG3, DG2DG3, dg3
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
desmocollin 1
|
| Other Description |
desmocollin-1|desmosomal glycoprotein 2/3
|
| Swissprots |
Q28095 Q01107
|
| Accessions |
CAA40289 DAA15966 Q01107 BC150133 AAI50134 M67489 AAA30492 X56966 CAA40286 X56967 CAA40287 X58029 CAA41088 XM_005223952 XP_005224009 NM_174044 NP_776469
|
| Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
|
| Tissue Specificity |
Epidermis and weakly in tongue papillae.
|