Gene Symbol | PLA2G12B |
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Entrez Gene | 84647 |
Alt Symbol | FKSG71, GXIIB, GXIIIsPLA2, PLA2G13 |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group XIIB |
Other Description | group XIIB secretory phospholipase A2-like protein|group XIII secreted phospholipase A2|group XIII secretory phospholipase A2-like protein|phospholipase A2, group XIII|sPLA2-GXIIB |
Swissprots | Q9BX93 B7ZL23 Q96Q99 Q52LB2 |
Accessions | CAD33385 EAW54464 EAW54465 EAW54466 Q9BX93 AF339053 AAL09472 AF349540 AAK30168 AK311349 AK313712 AY358032 AAQ92918 BC093996 AAH93996 BC111946 AAI11947 BC143532 AAI43533 BF939574 XM_005270243 XP_005270300 XM_005270244 XP_005270301 XM_005270245 XP_005270302 NM_032562 NP_115951 |
Function | Not known; does not seem to have catalytic activity. |
Subcellular Location | Secreted. |
Tissue Specificity | Strong expression in liver, small intestine and kidney. {ECO:0000269|PubMed:14516201}. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group XIIB sPLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-413682 from Santa Cruz Biotechnology
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group XIIB sPLA 2 HDR Plasmid (h) - sc-413682-HDR from Santa Cruz Biotechnology
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group XIIB sPLA 2 Double Nickase Plasmid (h) - sc-413682-NIC from Santa Cruz Biotechnology
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group XIIB sPLA 2 Double Nickase Plasmid (h2) - sc-413682-NIC-2 from Santa Cruz Biotechnology
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group XIIB sPLA 2 CRISPR Activation Plasmid (h) - sc-413682-ACT from Santa Cruz Biotechnology
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group XIIB sPLA 2 CRISPR Activation Plasmid (h2) - sc-413682-ACT-2 from Santa Cruz Biotechnology
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group XIIB sPLA 2 Lentiviral Activation Particles (h) - sc-413682-LAC from Santa Cruz Biotechnology
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group XIIB sPLA 2 Lentiviral Activation Particles (h2) - sc-413682-LAC-2 from Santa Cruz Biotechnology
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group XIIB sPLA 2 siRNA (h) - sc-90439 from Santa Cruz Biotechnology
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group XIIB sPLA 2 shRNA Plasmid (h) - sc-90439-SH from Santa Cruz Biotechnology
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group XIIB sPLA 2 shRNA (h) Lentiviral Particles - sc-90439-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16884 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16884 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03482 from Sigma-Aldrich
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PLA2G12B siRNA (Human) - CRJ3554 from Cohesion Biosciences
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PLA2G12B RNAi - H00084647-R01 from Novus Biologicals
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shRNA set against Human PLA2G12B (NM_032562.2) - SHH376688 from Creative biogene
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shRNA set against Human PLA2G12B(NM_032562.2) - SHR118676 from Creative biogene
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PLA2G12B shRNA Plasmid (Human) - CHJ3554 from Cohesion Biosciences
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PLA2G12B miRNA 3'UTR clone - MiUTR1H-07954 from Creative biogene
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