| Gene Symbol | ldlr-b |
|---|---|
| Entrez Gene | 373644 |
| Alt Symbol | LDL receptor-2, fhc, ldlcq2, ldlr, ldlr2-a |
| Species | Xenopus |
| Gene Type | protein-coding |
| Description | low density lipoprotein receptor |
| Other Description | LDL receptor 2|low density lipoprotein receptor-2|low-density lipoprotein receptor 2 |
| Swissprots | Q99088 |
| Accessions | Q99088 BC170522 AAI70522 BC170523 AAI70523 M62978 AAA49898 NM_001085642 NP_001079111 |
| Function | Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein. |
| Top Pathways | Endocytosis |