| Gene Symbol |
ldlr-b
|
| Entrez Gene |
373644
|
| Alt Symbol |
LDL receptor-2, fhc, ldlcq2, ldlr, ldlr2-a
|
| Species |
Xenopus
|
| Gene Type |
protein-coding
|
| Description |
low density lipoprotein receptor
|
| Other Description |
LDL receptor 2|low density lipoprotein receptor-2|low-density lipoprotein receptor 2
|
| Swissprots |
Q99088
|
| Accessions |
Q99088 BC170522 AAI70522 BC170523 AAI70523 M62978 AAA49898 NM_001085642 NP_001079111
|
| Function |
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
|
| Top Pathways |
Endocytosis
|