Gene Symbol | GP5 |
---|---|
Entrez Gene | 2814 |
Alt Symbol | CD42d, GPV |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein V (platelet) |
Other Description | glycoprotein 5|platelet glycoprotein V |
Swissprots | P40197 D1MER9 |
Accessions | ACZ44929 CAA80637 CBX54456 CDI44163 EAW78053 P40197 BC152810 AAI52811 L11238 AAA03069 NM_004488 NP_004479 |
Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Platelets and megakaryocytes. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
CD42d CRISPR/Cas9 KO Plasmid (h) - sc-404793 from Santa Cruz Biotechnology
|
||||||||
CD42d HDR Plasmid (h) - sc-404793-HDR from Santa Cruz Biotechnology
|
||||||||
CD42d Double Nickase Plasmid (h) - sc-404793-NIC from Santa Cruz Biotechnology
|
||||||||
CD42d Double Nickase Plasmid (h2) - sc-404793-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CD42d CRISPR Activation Plasmid (h) - sc-404793-ACT from Santa Cruz Biotechnology
|
||||||||
CD42d CRISPR Activation Plasmid (h2) - sc-404793-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CD42d Lentiviral Activation Particles (h) - sc-404793-LAC from Santa Cruz Biotechnology
|
||||||||
CD42d Lentiviral Activation Particles (h2) - sc-404793-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CD42d siRNA (h) - sc-61913 from Santa Cruz Biotechnology
|
||||||||
CD42d shRNA Plasmid (h) - sc-61913-SH from Santa Cruz Biotechnology
|
||||||||
CD42d shRNA (h) Lentiviral Particles - sc-61913-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN9497 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9497 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10599 from Sigma-Aldrich
|
||||||||
GP5 siRNA (Human) - CRH1881 from Cohesion Biosciences
|
||||||||
GP5 - MBS829512 from MyBioSource
|
||||||||
shRNA set against Human GP5 (NM_004488.2) - SHH305558 from Creative biogene
|
||||||||
shRNA set against Human GP5(NM_004488.2) - SHH095167 from Creative biogene
|
||||||||
Human GP5 siRNA - orb262383 from Biorbyt
|
||||||||
GP5 shRNA Plasmid (Human) - CHH1881 from Cohesion Biosciences
|
||||||||
GP5 miRNA 3'UTR clone - MiUTR1H-04152 from Creative biogene
|