Gene Symbol | SEC24B |
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Entrez Gene | 10427 |
Alt Symbol | SEC24 |
Species | Human |
Gene Type | protein-coding |
Description | SEC24 family member B |
Other Description | SEC24 related gene family, member B|protein transport protein Sec24B|secretory protein 24 |
Swissprots | Q0VG08 B7ZKM8 O95487 B7ZKN4 |
Accessions | EAX06241 O95487 AA194999 AI193145 AJ131245 CAA10335 AK300278 BAG62038 AK304234 BAG65103 BC040137 AAH40137 BC117135 AAI17136 BC143268 AAI43269 BC143269 BC143276 AAI43277 BM802180 DA498444 XM_005262688 XP_005262745 XM_005262691 XP_005262748 XM_011531534 XP_011529836 XM_011531535 XP_011529837 XM_011531536 XP_011529838 XM_011531537 XP_011529839 XM_011531538 XP_011529840 XM_011531539 XP_011529841 XM_011531540 XP_011529842 NM_001042734 NP_001036199 NM_001300813 NP_001287742 NM_006323 NP_006314 |
Function | Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. |
Subcellular Location | Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane {ECO:0000305}. Golgi apparatus membrane {ECO:0000250}. |
Tissue Specificity | Expressed in fibroblasts, hepatocytes, and lymphocytes. |
Top Pathways | Protein processing in endoplasmic reticulum |
SignalSilence ® Sec24B siRNA I - 12229 from Cell Signaling Technology
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SignalSilence ® Sec24B siRNA II - 12333 from Cell Signaling Technology
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Sec24B CRISPR/Cas9 KO Plasmid (h) - sc-408184 from Santa Cruz Biotechnology
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Sec24B HDR Plasmid (h) - sc-408184-HDR from Santa Cruz Biotechnology
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Sec24B Double Nickase Plasmid (h) - sc-408184-NIC from Santa Cruz Biotechnology
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Sec24B Double Nickase Plasmid (h2) - sc-408184-NIC-2 from Santa Cruz Biotechnology
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Sec24B CRISPR Activation Plasmid (h) - sc-408184-ACT from Santa Cruz Biotechnology
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Sec24B CRISPR Activation Plasmid (h2) - sc-408184-ACT-2 from Santa Cruz Biotechnology
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Sec24B Lentiviral Activation Particles (h) - sc-408184-LAC from Santa Cruz Biotechnology
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Sec24B Lentiviral Activation Particles (h2) - sc-408184-LAC-2 from Santa Cruz Biotechnology
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Sec24B siRNA (h) - sc-88987 from Santa Cruz Biotechnology
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Sec24B shRNA Plasmid (h) - sc-88987-SH from Santa Cruz Biotechnology
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Sec24B shRNA (h) Lentiviral Particles - sc-88987-V from Santa Cruz Biotechnology
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SEC24B RNAi - H00010427-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19034 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19034 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06626 from Sigma-Aldrich
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SEC24B siRNA (Human) - CRH7072 from Cohesion Biosciences
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SEC24B - MBS8205875 from MyBioSource
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shRNA set against Human Sec24b (NM_006323.2) - SHH403816 from Creative biogene
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shRNA set against Human SEC24B(NM_006323.2) - SHR211992 from Creative biogene
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shRNA set against Human SEC24B(NM_001042734.1) - SHR212010 from Creative biogene
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SEC24B shRNA Plasmid (Human) - CHH7072 from Cohesion Biosciences
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SEC24B miRNA 3'UTR clone - MiUTR1H-09230 from Creative biogene
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