Gene Symbol | ASPSCR1 |
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Entrez Gene | 79058 |
Alt Symbol | ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9 |
Species | Human |
Gene Type | protein-coding |
Description | alveolar soft part sarcoma chromosome region, candidate 1 |
Other Description | UBX domain protein 9|UBX domain-containing protein 9|alveolar soft part sarcoma chromosomal region candidate gene 1 protein|alveolar soft part sarcoma locus|renal cell carcinoma gene on chromosome 17|renal cell carcinoma, papillary, 17|renal papillary cell carcinoma protein 17|tether containing UBX domain for GLUT4 |
Swissprots | Q7Z6N7 A8K3K9 Q8WV59 Q9BZE9 Q96M40 Q96LS5 |
Accessions | EAW89731 Q9BZE9 AF324219 AAK08959 AK057403 BAB71472 AK057851 BAB71595 AK090682 AK126967 AK127159 AK127311 AK226086 AK290624 BAF83313 BC006152 AAH06152 BC018722 AAH18722 DQ892522 ABM83448 DQ895734 ABM86660 XM_011523601 XP_011521903 XM_011523602 XP_011521904 XM_011523603 XP_011521905 XM_011523604 XP_011521906 XM_011523605 XP_011521907 NM_001251888 NP_001238817 NM_024083 NP_076988 NR_045351 |
Function | Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT. {ECO:0000250, ECO:0000269|PubMed:23349634}. |
Subcellular Location | Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum- Golgi intermediate compartment membrane {ECO:0000269|PubMed:22207755}; Peripheral membrane protein. Cytoplasm {ECO:0000269|PubMed:23349634}. Nucleus {ECO:0000269|PubMed:23349634}. |
Tissue Specificity | Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas. {ECO:0000269|PubMed:11244503, ECO:0000269|PubMed:11358836}. |
Top Pathways | Transcriptional misregulation in cancer |
TUG CRISPR/Cas9 KO Plasmid (h) - sc-410616 from Santa Cruz Biotechnology
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TUG HDR Plasmid (h) - sc-410616-HDR from Santa Cruz Biotechnology
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TUG Double Nickase Plasmid (h) - sc-410616-NIC from Santa Cruz Biotechnology
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TUG Double Nickase Plasmid (h2) - sc-410616-NIC-2 from Santa Cruz Biotechnology
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TUG CRISPR Activation Plasmid (h) - sc-410616-ACT from Santa Cruz Biotechnology
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TUG CRISPR Activation Plasmid (h2) - sc-410616-ACT-2 from Santa Cruz Biotechnology
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TUG Lentiviral Activation Particles (h) - sc-410616-LAC from Santa Cruz Biotechnology
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TUG Lentiviral Activation Particles (h2) - sc-410616-LAC-2 from Santa Cruz Biotechnology
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TUG siRNA (h) - sc-72020 from Santa Cruz Biotechnology
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TUG shRNA Plasmid (h) - sc-72020-SH from Santa Cruz Biotechnology
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TUG shRNA (h) Lentiviral Particles - sc-72020-V from Santa Cruz Biotechnology
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TUG RNAi - H00079058-R01 from Novus Biologicals
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TUG RNAi - H00079058-R02 from Novus Biologicals
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MISSION® esiRNA - EHU091221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3612 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3612 from Sigma-Aldrich
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ASPSCR1 siRNA (Human) - CRJ2284 from Cohesion Biosciences
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ASPSCR1 - MBS8215533 from MyBioSource
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shRNA set against Human ASPSCR1 (NM_024083.3) - SHH241674 from Creative biogene
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Human ASPSCR1 siRNA - orb272785 from Biorbyt
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ASPSCR1 shRNA Plasmid (Human) - CHJ2284 from Cohesion Biosciences
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ASPSCR1 miRNA 3'UTR clone - MiUTR3H-08303 from Creative biogene
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