| Gene Symbol |
PGLYRP2
|
| Entrez Gene |
114770
|
| Alt Symbol |
HMFT0141, PGLYRPL, PGRP-L, PGRPL, TAGL-like, tagL, tagL-alpha, tagl-beta
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
peptidoglycan recognition protein 2
|
| Other Description |
N-acetylmuramoyl-L-alanine amidase|peptidoglycan recognition protein L|peptidoglycan recognition protein long
|
| Swissprots |
Q68CK1 A8K050 B7ZM33 Q96PD5 Q9UC60 B2RMZ2 A8K8C7 Q96N74
|
| Accessions |
EAW84482 EAW84483 Q96PD5 AB073610 BAD38647 AF384856 AAL05629 AK055882 BAB71034 AK289415 BAF82104 AK292292 BAF84981 AY358156 AAQ88523 BC136551 AAI36552 BC136552 AAI36553 BC144238 AAI44239 DB041324 XM_006722633 XP_006722696 NM_052890 NP_443122
|
| Function |
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. {ECO:0000269|PubMed:14506276}.
|
| Subcellular Location |
Secreted. Membrane.
|
| Tissue Specificity |
Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16054449}.
|
![Western Blot: PGRPL Overexpression Lysate (Adult Normal) [NBL1-14335] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PGRPL.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1415_PGRPL%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14335-img0002.jpg)