Gene Symbol | PHF12 |
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Entrez Gene | 57649 |
Alt Symbol | PF1 |
Species | Human |
Gene Type | protein-coding |
Description | PHD finger protein 12 |
Other Description | PHD factor 1|PHD zinc finger transcription factor |
Swissprots | Q9P205 Q9BV34 Q9H7U9 Q96QT6 Q6ZML2 Q2TAK2 Q0VAI5 |
Accessions | EAW51164 EAW51165 EAW51166 EAW51167 Q96QT6 AB040956 BAA96047 AK024290 BAB14875 AK091441 AK160370 BAD18713 AK291420 BAF84109 AK294056 BAG57403 AL161953 AY030283 AAK38349 BC001657 AAH01657 BC110882 AAI10883 BC121043 AAI21044 BC121044 AAI21045 XM_005258015 XP_005258072 XM_005258016 XP_005258073 XM_011525078 XP_011523380 XM_011525079 XP_011523381 XM_011525080 XP_011523382 XM_011525081 XP_011523383 XM_011525082 XP_011523384 XM_011525083 XP_011523385 NM_001033561 NP_001028733 NM_001290131 NP_001277060 NM_020889 NP_065940 |
Function | Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA. {ECO:0000269|PubMed:11390640, ECO:0000303|PubMed:11390640}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11390640}. |
PHF12 CRISPR/Cas9 KO Plasmid (h) - sc-410608 from Santa Cruz Biotechnology
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PHF12 HDR Plasmid (h) - sc-410608-HDR from Santa Cruz Biotechnology
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PHF12 Double Nickase Plasmid (h) - sc-410608-NIC from Santa Cruz Biotechnology
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PHF12 Double Nickase Plasmid (h2) - sc-410608-NIC-2 from Santa Cruz Biotechnology
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PHF12 CRISPR Activation Plasmid (h) - sc-410608-ACT from Santa Cruz Biotechnology
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PHF12 CRISPR Activation Plasmid (h2) - sc-410608-ACT-2 from Santa Cruz Biotechnology
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PHF12 Lentiviral Activation Particles (h) - sc-410608-LAC from Santa Cruz Biotechnology
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PHF12 Lentiviral Activation Particles (h2) - sc-410608-LAC-2 from Santa Cruz Biotechnology
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PHF12 siRNA (h) - sc-93900 from Santa Cruz Biotechnology
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PHF12 shRNA Plasmid (h) - sc-93900-SH from Santa Cruz Biotechnology
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PHF12 shRNA (h) Lentiviral Particles - sc-93900-V from Santa Cruz Biotechnology
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PF1 RNAi - H00057649-R01 from Novus Biologicals
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PF1 RNAi - H00057649-R02 from Novus Biologicals
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MISSION® esiRNA - EHU094811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16717 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16717 from Sigma-Aldrich
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PHF12 siRNA (Human) - CRJ1607 from Cohesion Biosciences
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shRNA set against Human PHF12 (NM_020889.2) - SHH374636 from Creative biogene
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shRNA set against Human PHF12(NM_001033561.1) - SHR110884 from Creative biogene
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PHF12 shRNA Plasmid (Human) - CHJ1607 from Cohesion Biosciences
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PHF12 miRNA 3'UTR clone - MiUTR1H-07847 from Creative biogene
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PHF12 miRNA 3'UTR clone - MiUTR1H-07848 from Creative biogene
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