Gene Symbol | PPP2R3A |
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Entrez Gene | 5523 |
Alt Symbol | PPP2R3, PR130, PR72 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, regulatory subunit B'', alpha |
Other Description | PP2A subunit B isoforms B72/B130|PP2A, subunit B, R3 isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and (PR 130), beta isoform|serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B|serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha |
Swissprots | Q9NPQ5 A8KAE7 Q06189 Q06190 B7ZAE3 B4DNU1 |
Accessions | EAW79122 EAW79123 EAW79124 EAW79125 EAW79126 Q06190 AK293012 BAF85701 AK298059 BAG60353 AK299544 BAG61490 AK302163 BAG63530 AK314243 BAG36910 AK316258 BAH14629 AL389975 CAB97532 AL599266 BC015034 AAH15034 BC029409 AAH29409 BC040158 BC065531 AAH65531 BE897340 DB223168 DB378665 L07590 AAB02613 L12146 AAB02614 XM_006713686 XP_006713749 XM_011512956 XP_011511258 XM_011512957 XP_011511259 NM_001190447 NP_001177376 NM_002718 NP_002709 NM_181897 NP_871626 |
Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, muscle and kidney. |
Top Pathways | mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway |
PPP2R3A CRISPR/Cas9 KO Plasmid (h) - sc-402433 from Santa Cruz Biotechnology
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PPP2R3A HDR Plasmid (h) - sc-402433-HDR from Santa Cruz Biotechnology
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PPP2R3A Double Nickase Plasmid (h) - sc-402433-NIC from Santa Cruz Biotechnology
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PPP2R3A Double Nickase Plasmid (h2) - sc-402433-NIC-2 from Santa Cruz Biotechnology
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PPP2R3A CRISPR Activation Plasmid (h) - sc-402433-ACT from Santa Cruz Biotechnology
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PPP2R3A CRISPR Activation Plasmid (h2) - sc-402433-ACT-2 from Santa Cruz Biotechnology
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PPP2R3A Lentiviral Activation Particles (h) - sc-402433-LAC from Santa Cruz Biotechnology
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PPP2R3A Lentiviral Activation Particles (h2) - sc-402433-LAC-2 from Santa Cruz Biotechnology
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PP2A-B72/B130 siRNA (h) - sc-106434 from Santa Cruz Biotechnology
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PP2A-B72/B130 shRNA Plasmid (h) - sc-106434-SH from Santa Cruz Biotechnology
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PP2A-B72/B130 shRNA (h) Lentiviral Particles - sc-106434-V from Santa Cruz Biotechnology
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PPP2R3A RNAi - H00005523-R03 from Novus Biologicals
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MISSION® esiRNA - EHU091911 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0627 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0626 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17295 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17295 from Sigma-Aldrich
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PPP2R3A siRNA (Human) - CRH3702 from Cohesion Biosciences
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PPP2R3A RNAi - H00005523-R04 from Novus Biologicals
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shRNA set against Human PPP2R3A (NM_181897.2) - SHH381432 from Creative biogene
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Human PPP2R3A siRNA - orb264204 from Biorbyt
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PPP2R3A shRNA Plasmid (Human) - CHH3702 from Cohesion Biosciences
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PPP2R3A miRNA 3'UTR clone - MiUTR4H-TG12199 from Creative biogene
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