Gene Symbol | Nfs1 |
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Entrez Gene | 18041 |
Alt Symbol | AA987187, m-Nfs1, m-Nfsl |
Species | Mouse |
Gene Type | protein-coding |
Description | nitrogen fixation gene 1 (S. cerevisiae) |
Other Description | cysteine desulfurase, mitochondrial|nifS-like (sic)|nitrogen fixation gene, yeast homolog 1 |
Swissprots | Q9Z1J3 Q8C6I5 |
Accessions | EDL06178 EDL06179 Q9Z1J3 AJ222660 CAA10916 AK003786 AK004077 BAB23157 AK005724 AK075575 BAC35831 AK084831 AK132838 BAE21386 AK148527 BAE28601 AK159828 BAE35407 AK181025 AK183689 AK188011 AK189862 AK191681 AK193838 AK198789 AK206231 AK206381 AK206572 AK207148 AK207847 AK207895 AK211411 AK211463 AK211628 AK212905 AK216163 AK220082 BC010586 AAH10586 BC012651 XM_006498897 XP_006498960 XM_011239348 XP_011237650 NM_010911 NP_035041 |
Function | Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron- sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Sulfur relay system, Thiamine metabolism |
NFS1 CRISPR/Cas9 KO Plasmid (m) - sc-421884 from Santa Cruz Biotechnology
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NFS1 HDR Plasmid (m) - sc-421884-HDR from Santa Cruz Biotechnology
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NFS1 Double Nickase Plasmid (m) - sc-421884-NIC from Santa Cruz Biotechnology
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NFS1 Double Nickase Plasmid (m2) - sc-421884-NIC-2 from Santa Cruz Biotechnology
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NFS1 CRISPR Activation Plasmid (m) - sc-421884-ACT from Santa Cruz Biotechnology
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NFS1 CRISPR Activation Plasmid (m2) - sc-421884-ACT-2 from Santa Cruz Biotechnology
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NFS1 Lentiviral Activation Particles (m) - sc-421884-LAC from Santa Cruz Biotechnology
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NFS1 Lentiviral Activation Particles (m2) - sc-421884-LAC-2 from Santa Cruz Biotechnology
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NFS1 siRNA (m) - sc-149946 from Santa Cruz Biotechnology
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NFS1 shRNA Plasmid (m) - sc-149946-SH from Santa Cruz Biotechnology
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NFS1 shRNA (m) Lentiviral Particles - sc-149946-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU048951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36414 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36414 from Sigma-Aldrich
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NFS1 siRNA (Mouse) - CRM2764 from Cohesion Biosciences
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shRNA set against Mouse NFS1 (NM_010911.2) - SHH351988 from Creative biogene
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shRNA set against Mouse Nfs1(NM_010911.2) - SHR001688 from Creative biogene
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NFS1 shRNA Plasmid (Mouse) - CHM2764 from Cohesion Biosciences
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NFS1 miRNA 3'UTR clone - MiUTR1M-07638 from Creative biogene
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