| Gene Symbol | PSMC4 |
|---|---|
| Entrez Gene | 5704 |
| Alt Symbol | MIP224, RPT3, S6, TBP-7, TBP7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| Other Description | 26S protease regulatory subunit 6B|26S proteasome AAA-ATPase subunit RPT3|MB67-interacting protein|Tat-binding protein 7|protease 26S subunit 6 |
| Swissprots | Q96FV5 Q9UEX3 Q9UBM3 P43686 |
| Accessions | AAD39267 EAW56928 EAW56929 P43686 AF020736 AAC32612 AF038965 AAC26843 AK290285 BAF82974 AK310135 AK313183 BAG36000 BC000343 AAH00343 BC010396 AAH10396 BC014488 AAH14488 BC018811 BI828251 BT007232 AAP35896 DQ891875 ABM82801 DQ894876 ABM85802 U27515 AAC99817 NM_006503 NP_006494 NM_153001 NP_694546 |
| Function | The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. {ECO:0000269|PubMed:8060531}. |
| Subcellular Location | Cytoplasm. Nucleus. |
| Top Pathways | Proteasome, Epstein-Barr virus infection |