| Gene Symbol |
IL15
|
| Entrez Gene |
3600
|
| Alt Symbol |
IL-15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 15
|
| Other Description |
interleukin-15
|
| Swissprots |
Q93058 Q495Z8 O00440 Q6FGX7 D3DNZ2 P40933 O43512 Q9UBA3
|
| Accessions |
CAA62616 CAJ13397 CAJ32191 CAL40354 CAS97649 CBI67687 CCA64045 EAX05083 EAX05084 EAX05085 EAX05086 EAX05087 P40933 AA897685 AF031167 AAB97518 AK122993 BAG53839 AK290619 BAF83308 AY720442 AAU21241 BC018149 AAH18149 BC100961 AAI00962 BC100962 AAI00963 BC100963 AAI00964 BX116580 CA443264 CR541980 CAG46777 CR542007 CAG46804 CX761071 CX785233 DQ890548 ABM92165 DQ893709 ABM84635 DQ893710 ABM84636 S81555 AAD15004 U14407 AAA21551 X94222 CAA63913 X94223 CAA63914 Z38000 CAA86100 NM_000585 NP_000576 NM_172175 NP_751915 NR_037840 NM_172174
|
| Function |
Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
|
| Subcellular Location |
Isoform IL15-S48AA: Secreted.
|
| Tissue Specificity |
Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15- S21AA is preferentially expressed in tissues such as testis and thymus.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis, HTLV-I infection
|
![Western Blot: IL15 Overexpression Lysate (Adult Normal) [NBL1-11907] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IL15.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2984_IL15%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11907-img0002.jpg)