Gene Symbol | FGF18 |
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Entrez Gene | 8817 |
Alt Symbol | FGF-18, ZFGF5 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 18 |
Other Description | - |
Swissprots | Q6UWF1 O76093 D3DQL7 |
Accessions | CAI53491 CAS03064 EAW61441 EAW61442 O76093 AB007422 BAA31986 AF075292 AAC62240 AF211188 AAF22977 AM393798 CAL38673 AY358811 AAQ89954 BC006245 AAH06245 BQ018759 BT019570 AAV38377 BT019571 AAV38378 DQ892736 ABM83662 DQ895983 ABM86909 NM_003862 NP_003853 NM_033649 |
Function | Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation. {ECO:0000269|PubMed:16597617}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-18 CRISPR/Cas9 KO Plasmid (h) - sc-402175 from Santa Cruz Biotechnology
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FGF-18 HDR Plasmid (h) - sc-402175-HDR from Santa Cruz Biotechnology
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FGF-18 Double Nickase Plasmid (h) - sc-402175-NIC from Santa Cruz Biotechnology
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FGF-18 Double Nickase Plasmid (h2) - sc-402175-NIC-2 from Santa Cruz Biotechnology
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FGF-18 CRISPR Activation Plasmid (h) - sc-402175-ACT from Santa Cruz Biotechnology
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FGF-18 CRISPR Activation Plasmid (h2) - sc-402175-ACT-2 from Santa Cruz Biotechnology
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FGF-18 Lentiviral Activation Particles (h) - sc-402175-LAC from Santa Cruz Biotechnology
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FGF-18 Lentiviral Activation Particles (h2) - sc-402175-LAC-2 from Santa Cruz Biotechnology
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FGF-18 siRNA (h) - sc-39478 from Santa Cruz Biotechnology
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FGF-18 shRNA Plasmid (h) - sc-39478-SH from Santa Cruz Biotechnology
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FGF-18 shRNA (h) Lentiviral Particles - sc-39478-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU140031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8653 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8653 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03883 from Sigma-Aldrich
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FGF18 siRNA (Human) - CRH5815 from Cohesion Biosciences
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FGF18 - MBS8226673 from MyBioSource
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shRNA set against Human FGF18 (NM_003862.2) - SHH294465 from Creative biogene
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Human FGF18 siRNA - orb266317 from Biorbyt
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FGF18 shRNA Plasmid (Human) - CHH5815 from Cohesion Biosciences
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FGF18 miRNA 3'UTR clone - MiUTR3H-06214 from Creative biogene
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