| Gene Symbol | HEXB |
|---|---|
| Entrez Gene | 3074 |
| Alt Symbol | ENC-1AS, HEL-248 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hexosaminidase B (beta polypeptide) |
| Other Description | HCC-7|N-acetyl-beta-glucosaminidase subunit beta|beta-N-acetylhexosaminidase subunit beta|beta-hexosaminidase subunit beta|cervical cancer proto-oncogene 7 protein|epididymis luminal protein 248|hexosaminidase subunit B |
| Swissprots | P07686 |
| Accessions | AAA52645 EAW95741 EAW95742 P07686 AF378118 AAM46114 AK122992 AK130002 AK130375 AY643499 AAV48875 BC017378 AAH17378 BE907813 BT009919 AAP88921 D10518 D10519 D10520 FJ224336 ACI46028 JF432353 ADZ15570 M13519 AAA51828 M19735 AAA68620 M34906 AAA51829 NM_000521 NP_000512 NM_001292004 NP_001278933 |
| Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. |
| Subcellular Location | Lysosome. |
| Top Pathways | Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation |