Gene Symbol |
HEXB
|
Entrez Gene |
3074
|
Alt Symbol |
ENC-1AS, HEL-248
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
hexosaminidase B (beta polypeptide)
|
Other Description |
HCC-7|N-acetyl-beta-glucosaminidase subunit beta|beta-N-acetylhexosaminidase subunit beta|beta-hexosaminidase subunit beta|cervical cancer proto-oncogene 7 protein|epididymis luminal protein 248|hexosaminidase subunit B
|
Swissprots |
P07686
|
Accessions |
AAA52645 EAW95741 EAW95742 P07686 AF378118 AAM46114 AK122992 AK130002 AK130375 AY643499 AAV48875 BC017378 AAH17378 BE907813 BT009919 AAP88921 D10518 D10519 D10520 FJ224336 ACI46028 JF432353 ADZ15570 M13519 AAA51828 M19735 AAA68620 M34906 AAA51829 NM_000521 NP_000512 NM_001292004 NP_001278933
|
Function |
Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
|
Subcellular Location |
Lysosome.
|
Top Pathways |
Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation
|