Gene Symbol | DRD5 |
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Entrez Gene | 1816 |
Alt Symbol | DBDR, DRD1B, DRD1L2 |
Species | Human |
Gene Type | protein-coding |
Description | dopamine receptor D5 |
Other Description | D(1B) dopamine receptor|D1beta dopamine receptor|d(5) dopamine receptor|dopamine D5 receptor|dopamine receptor D1B |
Swissprots | Q8NEQ8 P21918 B2R9S3 |
Accessions | AAA52329 CAA41360 EAW92679 P21918 AK313897 BAG36620 AY136750 AAN01276 BC009748 AAH09748 DQ891933 ABM82859 DQ895120 ABM86046 NM_000798 NP_000789 |
Function | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. {ECO:0000269|PubMed:1834671}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Neuron-specific, localized primarily within limbic regions of the brain. {ECO:0000269|PubMed:1834671}. |
Top Pathways | Calcium signaling pathway, Dopaminergic synapse, cAMP signaling pathway, Neuroactive ligand-receptor interaction |
D5DR CRISPR/Cas9 KO Plasmid (h) - sc-404047 from Santa Cruz Biotechnology
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D5DR HDR Plasmid (h) - sc-404047-HDR from Santa Cruz Biotechnology
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D5DR Double Nickase Plasmid (h) - sc-404047-NIC from Santa Cruz Biotechnology
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D5DR Double Nickase Plasmid (h2) - sc-404047-NIC-2 from Santa Cruz Biotechnology
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D5DR CRISPR Activation Plasmid (h) - sc-404047-ACT from Santa Cruz Biotechnology
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D5DR CRISPR Activation Plasmid (h2) - sc-404047-ACT-2 from Santa Cruz Biotechnology
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D5DR Lentiviral Activation Particles (h) - sc-404047-LAC from Santa Cruz Biotechnology
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D5DR Lentiviral Activation Particles (h2) - sc-404047-LAC-2 from Santa Cruz Biotechnology
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D5DR siRNA (h) - sc-41934 from Santa Cruz Biotechnology
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D5DR shRNA Plasmid (h) - sc-41934-SH from Santa Cruz Biotechnology
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D5DR shRNA (h) Lentiviral Particles - sc-41934-V from Santa Cruz Biotechnology
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Dopamine D5 R/DRD5 RNAi - H00001816-R02 from Novus Biologicals
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MISSION® esiRNA - EHU139051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1817 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1817 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04169 from Sigma-Aldrich
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DRD5 siRNA (Human) - CRH1267 from Cohesion Biosciences
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DRD5 - MBS8241006 from MyBioSource
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shRNA set against Human DRD5 (NM_000798.4) - SHH281057 from Creative biogene
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Human DRD5 siRNA - orb261769 from Biorbyt
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DRD5 shRNA Plasmid (Human) - CHH1267 from Cohesion Biosciences
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