Gene Symbol |
COMMD10
|
Entrez Gene |
51397
|
Alt Symbol |
PTD002
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
COMM domain containing 10
|
Other Description |
COMM domain-containing protein 10
|
Swissprots |
D3DT07 Q9Y6G5 Q9P077
|
Accessions |
EAW48941 EAW48942 EAW48943 Q9Y6G5 AF078857 AAD44489 AF161423 AAF28983 AK002147 BAA92108 AW128995 AW662195 AY542165 AAS22247 BC005179 AAH05179 BI859871 DA001572 HQ447152 ADQ31639 HY139221 XM_011543458 XP_011541760 XM_011543459 XP_011541761 XM_011543460 XP_011541762 XM_011543461 XP_011541763 XM_011543462 XP_011541764 XM_011549014 XP_011547316 XR_948268 XR_948269 XR_948270 XR_948271 XR_948272 NM_001308080 NP_001295009 NM_016144 NP_057228
|
Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
|
Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:15799966}.
|