Cyp46a1

Gene Symbol Cyp46a1
Entrez Gene 13116
Alt Symbol Cyp46
Species Mouse
Gene Type protein-coding
Description cytochrome P450, family 46, subfamily a, polypeptide 1
Other Description CH24H|cholesterol 24-hydroxylase|cholestrol 24-hydroxylase|cytochrome P450 46A1|cytochrome P450, 46 (cholesterol 24-hydroxylase)|cytochrome P450, 46a1 (cholesterol 24-hydroxylase)
Swissprots Q9WVK8
Accessions EDL18715 EDL18716 Q9WVK8 AF094479 AAD41243 AK140740 BAE24462 BC018307 AAH18307 XM_006515456 XP_006515519 XR_381477 NM_010010 NP_034140
Function Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds.
Subcellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Tissue Specificity Expressed in high level in brain (cerebral cortex, hippocampus, dentate gyrus and thalamus) and in lower levels in testis and liver. Brain's expression increased linearly with age.
Top Pathways Primary bile acid biosynthesis

CYP46 CRISPR/Cas9 KO Plasmid (m) - sc-419926 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 HDR Plasmid (m) - sc-419926-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 Double Nickase Plasmid (m) - sc-419926-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 Double Nickase Plasmid (m2) - sc-419926-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 CRISPR Activation Plasmid (m) - sc-419926-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 CRISPR Activation Plasmid (m2) - sc-419926-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 Lentiviral Activation Particles (m) - sc-419926-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 Lentiviral Activation Particles (m2) - sc-419926-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CYP46 siRNA (m) - sc-77076 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CYP46 shRNA Plasmid (m) - sc-77076-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CYP46 shRNA (m) Lentiviral Particles - sc-77076-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU041091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN29562 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29562 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CYP46A1 siRNA (Mouse) - CRM0954 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CYP46A1 - MBS8238974 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse CYP46A1 (NM_010010.1) - SHH273537 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Cyp46a1(NM_010010.1) - SHG207187 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse CYP46A1 siRNA - orb280430 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CYP46A1 shRNA Plasmid (Mouse) - CHM0954 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

CYP46A1 miRNA 3'UTR clone - MiUTR1M-03550 from Creative biogene

Species Reactivities Mouse
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