| Gene Symbol | SAR1B |
|---|---|
| Entrez Gene | 51128 |
| Alt Symbol | ANDD, CMRD, GTBPB, SARA2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | secretion associated, Ras related GTPase 1B |
| Other Description | 2310075M17Rik|GTP-binding protein B|GTP-binding protein SAR1b|GTP-binding protein Sara|SAR1 homolog B|SAR1a gene homolog 2 |
| Swissprots | Q567T4 Q9Y6B6 D3DQA4 |
| Accessions | CAG32967 EAW62249 EAW62250 Q9Y6B6 AF087850 AAP97161 AF092130 AAD40372 AK056821 BAG51815 AK223452 BAD97172 AL512710 CAC21652 AL710660 BC002847 AAH02847 BC093034 AAH93034 BM765118 CD048852 EU832499 ACE87671 EU832580 ACE86982 NM_001033503 NP_001028675 NM_016103 NP_057187 |
| Function | Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. {ECO:0000250}. |
| Tissue Specificity | Expressed in many tissues including small intestine, liver, muscle and brain. |
| Top Pathways | Protein processing in endoplasmic reticulum, Legionellosis |