Gene Symbol |
lias
|
Entrez Gene |
393528
|
Alt Symbol |
LS, zgc:66080
|
Species |
Zebrafish
|
Gene Type |
protein-coding
|
Description |
lipoic acid synthetase
|
Other Description |
LS|lipoyl synthase, mitochondrial
|
Swissprots |
Q6PHG4 A8WGN4
|
Accessions |
CBN72415 Q6PHG4 BC056561 AAH56561 BC154781 AAI54782 NM_001110401 NP_001103871
|
Function |
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
|
Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
|
Top Pathways |
Lipoic acid metabolism
|