| Gene Symbol |
GRHPR
|
| Entrez Gene |
9380
|
| Alt Symbol |
GLXR, GLYD, PH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glyoxylate reductase/hydroxypyruvate reductase
|
| Other Description |
glycerate-2-dehydrogenase
|
| Swissprots |
Q9UKX1 Q9H3E9 Q9UBQ7 Q5T945 Q9H636
|
| Accessions |
AAD46517 EAW58283 EAW58284 EAW58285 EAW58286 Q9UBQ7 AF113215 AAG39286 AF113251 AAD54066 AF134895 AAF00111 AF146018 AAD45886 AK024386 AK025978 AK026287 BAB15430 AK026752 AK307325 AK307902 AK315690 BAG38053 AM393403 CAL38281 AM393629 CAL38505 BC000605 AAH00605 BC003131 BC088360 AAH88360 XM_005251631 XP_005251688 XM_011518073 XP_011516375 XR_929374 NM_012203 NP_036335
|
| Function |
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
|
| Tissue Specificity |
Ubiquitous. Most abundantly expressed in the liver. {ECO:0000269|PubMed:10679197}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Pyruvate metabolism, Glyoxylate and dicarboxylate metabolism
|
![Western Blot: GRHPR Overexpression Lysate (Adult Normal) [NBL1-11334] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GRHPR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/19320_GRHPR%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-11334-img0002.jpg)