Gene Symbol | CLCF1 |
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Entrez Gene | 23529 |
Alt Symbol | BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6 |
Species | Human |
Gene Type | protein-coding |
Description | cardiotrophin-like cytokine factor 1 |
Other Description | B-cell stimulating factor 3|B-cell stimulatory factor 3|B-cell-stimulating factor 3|CRLF1 associated cytokine-like factor 1|neurotrophin-1/B-cell stimulating factor-3|novel neurotrophin-1 |
Swissprots | Q9UBD9 B4DNT4 Q6NZA4 |
Accessions | AAF00992 CAV33841 EAW74601 EAW74602 Q9UBD9 AF172854 AAD54284 AF176911 AAF00991 AK298052 BAG60346 AY049779 AAL15436 BC012939 AAH12939 BC066229 AAH66229 BC066230 AAH66230 BC066231 AAH66231 BM846622 DC393345 DQ891525 ABM82451 DQ894715 ABM85641 NM_001166212 NP_001159684 NM_013246 NP_037378 |
Function | Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver. {ECO:0000269|PubMed:10448081, ECO:0000269|PubMed:10500198}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
NNT-1/BSF-3 CRISPR/Cas9 KO Plasmid (h) - sc-404949 from Santa Cruz Biotechnology
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NNT-1/BSF-3 HDR Plasmid (h) - sc-404949-HDR from Santa Cruz Biotechnology
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NNT-1/BSF-3 Double Nickase Plasmid (h) - sc-404949-NIC from Santa Cruz Biotechnology
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NNT-1/BSF-3 Double Nickase Plasmid (h2) - sc-404949-NIC-2 from Santa Cruz Biotechnology
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NNT-1/BSF-3 CRISPR Activation Plasmid (h) - sc-404949-ACT from Santa Cruz Biotechnology
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NNT-1/BSF-3 CRISPR Activation Plasmid (h2) - sc-404949-ACT-2 from Santa Cruz Biotechnology
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NNT-1/BSF-3 Lentiviral Activation Particles (h) - sc-404949-LAC from Santa Cruz Biotechnology
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NNT-1/BSF-3 Lentiviral Activation Particles (h2) - sc-404949-LAC-2 from Santa Cruz Biotechnology
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NNT-1/BSF-3 siRNA (h) - sc-39685 from Santa Cruz Biotechnology
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NNT-1/BSF-3 shRNA Plasmid (h) - sc-39685-SH from Santa Cruz Biotechnology
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NNT-1/BSF-3 shRNA (h) Lentiviral Particles - sc-39685-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU045961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6168 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6168 from Sigma-Aldrich
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CLCF1 siRNA (Human) - CRH8334 from Cohesion Biosciences
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CLCF1 - MBS8232449 from MyBioSource
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shRNA set against Human CLCF1 (NM_013246.2) - SHH264542 from Creative biogene
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shRNA set against Human CLCF1(NM_013246.2) - SHG179917 from Creative biogene
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Human CLCF1 siRNA - orb268836 from Biorbyt
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CLCF1 shRNA Plasmid (Human) - CHH8334 from Cohesion Biosciences
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CLCF1 miRNA 3'UTR clone - MiUTR1H-02183 from Creative biogene
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