Gene Symbol | SREK1 |
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Entrez Gene | 140890 |
Alt Symbol | SFRS12, SRrp508, SRrp86 |
Species | Human |
Gene Type | protein-coding |
Description | splicing regulatory glutamine/lysine-rich protein 1 |
Other Description | serine-arginine-rich splicing regulatory protein 508|serine/arginine-rich-splicing regulatory protein 86|splicing factor, arginine/serine-rich 12|splicing regulatory protein 508 |
Swissprots | A4FTW3 Q2M1J0 Q86X37 Q8WXA9 |
Accessions | EAW51328 EAW51329 EAW51330 EAW51331 Q8WXA9 AB209694 BAD92931 AF459094 AAL67778 AK091758 BAG52411 AK125893 AK308287 AL049309 AL703981 AL832888 CAH10414 AW963850 BC017000 BC047322 AAH47322 BC067770 AAH67770 BC112343 AAI12344 CD706234 XM_005248439 XP_005248496 XM_005248440 XP_005248497 XM_005248442 XP_005248499 XM_006714535 XP_006714598 XM_011543170 XP_011541472 XM_011543171 XP_011541473 XR_948236 NM_001077199 NP_001070667 NM_001270492 NP_001257421 NM_001270493 NP_001257422 NM_139168 NP_631907 |
Function | Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
SFRS12 CRISPR/Cas9 KO Plasmid (h) - sc-407691 from Santa Cruz Biotechnology
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SFRS12 HDR Plasmid (h) - sc-407691-HDR from Santa Cruz Biotechnology
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SFRS12 Double Nickase Plasmid (h) - sc-407691-NIC from Santa Cruz Biotechnology
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SFRS12 Double Nickase Plasmid (h2) - sc-407691-NIC-2 from Santa Cruz Biotechnology
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SFRS12 CRISPR Activation Plasmid (h) - sc-407691-ACT from Santa Cruz Biotechnology
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SFRS12 CRISPR Activation Plasmid (h2) - sc-407691-ACT-2 from Santa Cruz Biotechnology
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SFRS12 Lentiviral Activation Particles (h) - sc-407691-LAC from Santa Cruz Biotechnology
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SFRS12 Lentiviral Activation Particles (h2) - sc-407691-LAC-2 from Santa Cruz Biotechnology
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SFRS12 siRNA (h) - sc-91849 from Santa Cruz Biotechnology
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SFRS12 shRNA Plasmid (h) - sc-91849-SH from Santa Cruz Biotechnology
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SFRS12 shRNA (h) Lentiviral Particles - sc-91849-V from Santa Cruz Biotechnology
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SFRS12 RNAi - H00140890-R01 from Novus Biologicals
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MISSION® esiRNA - EHU068171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20565 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20565 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10996 from Sigma-Aldrich
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SREK1 siRNA (Human) - CRJ5344 from Cohesion Biosciences
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SREK1 - MBS8212383 from MyBioSource
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shRNA set against Human SREK1 (NM_139168.3) - SHH417752 from Creative biogene
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Human SREK1 siRNA - orb275845 from Biorbyt
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SREK1 shRNA Plasmid (Human) - CHJ5344 from Cohesion Biosciences
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SREK1 miRNA 3'UTR clone - MiUTR4H-TG07990 from Creative biogene
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