Gene Symbol | ABCA6 |
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Entrez Gene | 23460 |
Alt Symbol | EST155051 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 6 |
Other Description | ABC transporter ABCA6|ATP-binding cassette A6|ATP-binding cassette sub-family A member 6 |
Swissprots | Q8WWZ6 Q8N856 Q8N139 Q6NSH9 |
Accessions | AAM77558 Q8N139 AF373290 AAM77557 AK097296 BAC04994 AK125487 BAG54204 AK308431 AY028898 AAK30023 BC029852 BC070125 AAH70125 BC125231 AAI25232 BC125232 AAI25233 BC166682 AAI66682 BX647672 U66680 XM_006721791 XP_006721854 XM_006721793 XP_006721856 XM_011524573 XP_011522875 XM_011524574 XP_011522876 NM_080284 NP_525023 NM_172346 |
Function | Probable transporter which may play a role in macrophage lipid homeostasis. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed with higher expression in liver. {ECO:0000269|PubMed:11478798, ECO:0000269|Ref.2}. |
Top Pathways | ABC transporters |
ABCA6 CRISPR/Cas9 KO Plasmid (h) - sc-411744 from Santa Cruz Biotechnology
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ABCA6 HDR Plasmid (h) - sc-411744-HDR from Santa Cruz Biotechnology
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ABCA6 Double Nickase Plasmid (h) - sc-411744-NIC from Santa Cruz Biotechnology
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ABCA6 Double Nickase Plasmid (h2) - sc-411744-NIC-2 from Santa Cruz Biotechnology
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ABCA6 CRISPR Activation Plasmid (h) - sc-411744-ACT from Santa Cruz Biotechnology
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ABCA6 CRISPR Activation Plasmid (h2) - sc-411744-ACT-2 from Santa Cruz Biotechnology
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ABCA6 Lentiviral Activation Particles (h) - sc-411744-LAC from Santa Cruz Biotechnology
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ABCA6 Lentiviral Activation Particles (h2) - sc-411744-LAC-2 from Santa Cruz Biotechnology
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ABCA6 siRNA (h) - sc-93825 from Santa Cruz Biotechnology
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ABCA6 shRNA Plasmid (h) - sc-93825-SH from Santa Cruz Biotechnology
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ABCA6 shRNA (h) Lentiviral Particles - sc-93825-V from Santa Cruz Biotechnology
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ABCA6 RNAi - H00023460-R06 from Novus Biologicals
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ABCA6 RNAi - H00023460-R05 from Novus Biologicals
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MISSION® esiRNA - EHU095731 from Sigma-Aldrich
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MISSION® esiRNA - EHU095781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2623 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2623 from Sigma-Aldrich
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ABCA6 siRNA (Human) - CRH8282 from Cohesion Biosciences
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ABCA6 - MBS8221639 from MyBioSource
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shRNA set against Human ABCA6 (NM_080284.2) - SHH228886 from Creative biogene
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ABCA6 shRNA Plasmid (Human) - CHH8282 from Cohesion Biosciences
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ABCA6 miRNA 3'UTR clone - MiUTR1H-00023 from Creative biogene
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